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Advances in Radiotherapy
            & Nuclear Medicine                                    CS@LGG for acute radiation-induced bowel injury alleviation



               Abnormal intestinal motor patterns explain enteric   as biomaterials. Prog Polym Sci. 2004;29:887-908.
               colonization with gram-negative bacilli in late radiation      doi: 10.1016/j.progpolymsci.2004.04.001
               enteropathy. Gastroenterology. 1995;109:1078-1089.
                                                               23.  Fernandez JG, Ingber DE. Chitosan‐fibroin laminates:
               doi: 10.1016/0016-5085(95)90565-0
                                                                  Unexpected  strength  and  toughness  in  chitosan‐
            12.  Hauer-Jensen M, Denham JW, Andreyev HJN. Radiation   fibroin laminates inspired by insect cuticle.  Adv Mater.
               enteropathy-pathogenesis, treatment and prevention.  Nat   2012;24:480-484.
               Rev Gastroenterol Hepatol. 2014;11:470-479.
                                                                  doi: 10.1002/adma.201290016
               doi: 10.1038/nrgastro.2014.46
                                                               24.  Townsend S, Santos C, Baker S. Su1194 Novel therapeutic
            13.  Thomas H. FMT for drug-induced colitis.  Nat Rev   for the repair of gastrointestinal radiation injury.
               Gastroenterol Hepatol. 2018;16:4.                  Gastroenterology. 2016;150:S492.
               doi: 10.1038/s41575-018-0092-8                     doi: 10.1016/s0016-5085(16)31693-6
            14.  Lavelle  A,  Sokol  H.  Understanding  and  predicting  the   25.  Li H, Zhao S, Jiang M, et al. Biomodified extracellular vesicles
               efficacy of FMT. Nat Med. 2022;28:1759-1760.       remodel the intestinal microenvironment to overcome
                                                                  radiation enteritis. ACS Nano. 2023;17:14079-14098.
               doi: 10.1038/s41591-022-01991-0
                                                                  doi: 10.1021/acsnano.3c04578
            15.  Aumpan N, Chonprasertsuk S, Pornthisarn B,  et al.
               Tu1644 long-term efficacy and safety of encapsulated fecal   26.  Zhang D, Zhong D, Ouyang J,  et al. Microalgae-based
               microbiota transplantation (FMT) and FMT via rectal   oral microcarriers for gut microbiota homeostasis and
               enema for irritable bowel syndrome (IBS): A  prospective   intestinal protection in cancer radiotherapy. Nat Commun.
               cohort study. Gastroenterology. 2024;166:S1361-S1362.  2022;13:1413.
               doi: 10.1016/s0016-5085(24)03581-9                 doi: 10.1038/s41467-022-28744-4
            16.  Cammarota G, Ianiro G. FMT for ulcerative colitis: Closer   27.  Feng Y, Luo X, Li Z,  et al. A  ferroptosis-targeting ceria
               to the turning point.  Nat Rev Gastroenterol Hepatol.   anchored halloysite as orally drug delivery system for
               2019;16:266-268.                                   radiation colitis therapy. Nat Commun. 2023;14:5083.
               doi: 10.1038/s41575-019-0131-0                     doi: 10.1038/s41467-023-40794-w
            17.  Schnadower D, Tarr PI, Casper TC,  et al.  Lactobacillus   28.  Han K, Xie F, Animasahun O, et al. Inulin-gel-based oral
               rhamnosus GG versus placebo for acute gastroenteritis in   immunotherapy remodels the small intestinal microbiome
               children. N Engl J Med. 2018;379:2002-2014.        and suppresses food allergy. Nat Mater. 2024;23:1444-1455.
               doi: 10.1056/nejmoa1802598                         doi: 10.1038/s41563-024-01909-w
            18.  Sánchez B. Bile acid-microbiota crosstalk in gastrointestinal   29.  Liu Y, Tan Y, Cheng G, et al. Customized intranasal hydrogel
               inflammation and carcinogenesis: A role for bifidobacteria   delivering methylene blue ameliorates cognitive dysfunction
               and lactobacilli? Nat Rev Gastroenterol Hepatol. 2018;15:205.  against Alzheimer’s disease. Adv Mater. 2024;36:e2307081.
               doi: 10.1038/nrgastro.2018.23                      doi: 10.1002/adma.202307081
            19.  Isolauri E, Majamaa H, Arvola T, Rantala I, Virtanen  E,   30.  Pagels RF, Prud’homme RK. Polymeric nanoparticles and
               Arvilommi H.  Lactobacillus casei strain GG reverses   microparticles for the delivery of peptides, biologics, and
               increased intestinal permeability induced by cow milk in   soluble therapeutics. J Control Release. 2015;219:519-535.
               suckling rats. Gastroenterology. 1993;105:1643-1650.
                                                                  doi: 10.1016/j.jconrel.2015.09.001
               doi: 10.1016/0016-5085(93)91059-q
                                                               31.  Zhang J, Ou A, Tang X,  et al. “Two-birds-one-stone”
            20.  Qing  Z,  Yijun  C,  Pingdong  W,  Yi  Z,  Chaoji  C,  Jie  C.   colon-targeted nanomedicine treats ulcerative colitis via
               Extremely strong and tough chitosan films mediated by   remodeling immune microenvironment and anti-fibrosis.
               unique hydrated chitosan crystal structures. Mater Today.   J Nanobiotechnol. 2022;20:389.
               2021;51:27-38.
                                                                  doi: 10.1186/s12951-022-01598-0
               doi: 10.1016/j.mattod.2021.10.030
                                                               32.  Cook MT, Smith SL, Khutoryanskiy VV. Novel glycopolymer
            21.  Kesharwani P, Halwai K, Jha SK,  et al. Folate-engineered   hydrogels as mucosa-mimetic materials to reduce animal
               chitosan  nanoparticles:  Next-generation  anticancer  testing. Chem Commun. 2015;51:14447-14450.
               nanocarriers. Mol Cancer. 2024;23:244.
                                                                  doi: 10.1039/c5cc02428e
               doi: 10.1186/s12943-024-02163-z
                                                               33.  Zhong Y, Seidi F, Wang Y, Zheng L, Jin Y, Xiao H. Injectable
            22.  Sashiwa H, Aiba SI. Chemically modified chitin and chitosan   chitosan hydrogels tailored with antibacterial and


            Volume 3 Issue 3 (2025)                         80                        doi: 10.36922/ARNM025230026
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