Page 25 - BH-1-2
P. 25

Brain & Heart                                                       Pemafibrate in patients with dyslipidemia



            risk of bias. These RCTs exhibited a high level of quality   comparable-weight studies converging toward the pooled
            and, on the whole, presented a low risk of bias (Figure 21).   effect size of treatment as weight increased. The pattern
            The funnel plot demonstrated a symmetric distribution of   indicates no evidence of publication bias.











            Figure 18. Significantly lower non-high-density lipoprotein levels following treatment with pemafibrate at 0.1 mg/day.











            Figure 19. Significantly lower low-density lipoprotein levels in the placebo group when compared to those treated with pemafibrate at 0.1 mg/day.










            Figure 20. No difference in total cholesterol levels between groups.



































            Figure 21. Risk of bias summary for randomized studies (RoB 2).


            Volume 1 Issue 2 (2023)                         9                         https://doi.org/10.36922/bh.1629
   20   21   22   23   24   25   26   27   28   29   30