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Brain & Heart                                                    Surviving rhino-orbital-cerebral mucormycosis




            Table 1. Summary of literature on rhino-orbito-cerebral   Availability of data
            mucormycosis in immunocompetent patients published in
            PubMed                                             The data that support the study is available in the medical
                                                               record section of the department of neurosurgery, King
            Literature          Number  Survival outcomes      George’s  Medical  University.  Data  are  available  with  the
                                of cases                       permission of department of neurosurgery, King George’s
            Fairley et al. 11     1    Survived                Medical University. Medical University (URL: https://
            Garcia-Covarrubias et al. 12  1  Survived          kgns.in/).
            Chakrabarti et al. 13  1   Survived
            Rao et al. (2006) 14  5    Four survived, and one died  References
            Schütz et al. 15      1    Died                    1.   Bodenstein NP, McIntosh WA, Vlantis AC, Urquhart AC.
            Bhadani et al. 16     1    Survived                   Clinical signs of orbital ischemia in rhino-orbitocerebral
                                                                  mucormycosis. Laryngoscope. 1993;103:1357-1361.
            Baradkar et al. 17    1    Died
                                                                  doi: 10.1288/00005537-199312000-00007

            registry. It is imperative for every apex institute  in our   2.   Chakrabarti A, Das A, Mandal J, et al. The rising trend of
            country to establish similar measures.                invasive zygomycosis in patients with uncontrolled diabetes
                                                                  mellitus. Med Mycol. 2006;44:335-342.
            4. Conclusion                                         doi: 10.1080/13693780500464930
            This case report serves as a valuable addition to the   3.   Kauffman CA. Zygomycosis: Reemergence of an old
            understanding  of  ROCM    in  immunocompetent        pathogen. Clin Infect Dis. 2004;39:588-590.
            individuals. The meticulous documentation of the patient’s      doi: 10.1086/422729
            journey through this disease highlights the challenges in
            diagnosis and treatment and the importance of considering   4.   Chakrabarti A, Das A, Sharma A, et al. Ten years’ experience
            the extent of surgical intervention. In addition, it reinforces   in zygomycosis at a tertiary care centre in India.  J  Infect.
            the  importance  of  post-COVID-19  recovery  follow-up   2001;42:261-266.
            care among patients.                                  doi: 10.1053/jinf.2001.0831

            Acknowledgments                                    5.   Ribes JA, Vanover-Sams CL, Baker DJ. Zygomycetes in
                                                                  human disease. Clin Microbiol Rev. 2000;13:236-301.
            None.                                                 doi: 10.1128/CMR.13.2.236
            Funding                                            6.   Roden MM, Zaoutis TE, Buchanan WL, et al. Epidemiology
                                                                  and outcome of zygomycosis: A  review of 929 reported
            None.                                                 cases. Clin Infect Dis. 2005;41:634-653.
            Conflict of interest                                  doi: 10.1086/432579
            The authors declare no conflicts of interest.      7.   Spellberg B, Edwards J Jr., Ibrahim A. Novel perspectives
                                                                  on mucormycosis:  Pathophysiology, presentation, and
            Author contributions                                  management. Clin Microbiol Rev. 2005;18:556-569.
            Conceptualization: Bal Krishna Ojha                   doi: 10.1128/CMR.18.3.556-569.2005
            Investigation: Rajat Verma                         8.   Singh V, Singh M, Joshi C, Sangwan J. Rhinocerebral
            Methodology: Awdhesh Yadav                            mucormycosis in a patient with type 1 diabetes presenting
            Writing-original draft: Rajat Verma                   as toothache: A case report from Himalayan region of India.
            Writing-review & editing: Rajat Verma                 BMJ Case Rep. 2013;2013:bcr2013200811.
                                                                  doi: 10.1136/bcr-2013-200811
            Ethics approval and consent to participate
                                                               9.   Sen M, Honavar SG, Bansal R, et al. Epidemiology, clinical
            A written informed consent was taken from the patient   profile, management, and outcome of COVID-19-associated
            before writing the case report.                       rhino-orbital-cerebral mucormycosis in 2826  patients in
                                                                  India  -  Collaborative OPAI-IJO study on Mucormycosis
            Consent for publication                               in  COVID-19  (COSMIC),  report  1.  Indian J Ophthalmol.

            An informed consent was taken for publishing the patient   2021;69(7):1670-1692.
            data.                                                 doi: 10.4103/ijo.IJO_1565_21


            Volume 2 Issue 2 (2024)                         6                                doi: 10.36922/bh.2083
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