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Brain & Heart Surviving rhino-orbital-cerebral mucormycosis
Table 1. Summary of literature on rhino-orbito-cerebral Availability of data
mucormycosis in immunocompetent patients published in
PubMed The data that support the study is available in the medical
record section of the department of neurosurgery, King
Literature Number Survival outcomes George’s Medical University. Data are available with the
of cases permission of department of neurosurgery, King George’s
Fairley et al. 11 1 Survived Medical University. Medical University (URL: https://
Garcia-Covarrubias et al. 12 1 Survived kgns.in/).
Chakrabarti et al. 13 1 Survived
Rao et al. (2006) 14 5 Four survived, and one died References
Schütz et al. 15 1 Died 1. Bodenstein NP, McIntosh WA, Vlantis AC, Urquhart AC.
Bhadani et al. 16 1 Survived Clinical signs of orbital ischemia in rhino-orbitocerebral
mucormycosis. Laryngoscope. 1993;103:1357-1361.
Baradkar et al. 17 1 Died
doi: 10.1288/00005537-199312000-00007
registry. It is imperative for every apex institute in our 2. Chakrabarti A, Das A, Mandal J, et al. The rising trend of
country to establish similar measures. invasive zygomycosis in patients with uncontrolled diabetes
mellitus. Med Mycol. 2006;44:335-342.
4. Conclusion doi: 10.1080/13693780500464930
This case report serves as a valuable addition to the 3. Kauffman CA. Zygomycosis: Reemergence of an old
understanding of ROCM in immunocompetent pathogen. Clin Infect Dis. 2004;39:588-590.
individuals. The meticulous documentation of the patient’s doi: 10.1086/422729
journey through this disease highlights the challenges in
diagnosis and treatment and the importance of considering 4. Chakrabarti A, Das A, Sharma A, et al. Ten years’ experience
the extent of surgical intervention. In addition, it reinforces in zygomycosis at a tertiary care centre in India. J Infect.
the importance of post-COVID-19 recovery follow-up 2001;42:261-266.
care among patients. doi: 10.1053/jinf.2001.0831
Acknowledgments 5. Ribes JA, Vanover-Sams CL, Baker DJ. Zygomycetes in
human disease. Clin Microbiol Rev. 2000;13:236-301.
None. doi: 10.1128/CMR.13.2.236
Funding 6. Roden MM, Zaoutis TE, Buchanan WL, et al. Epidemiology
and outcome of zygomycosis: A review of 929 reported
None. cases. Clin Infect Dis. 2005;41:634-653.
Conflict of interest doi: 10.1086/432579
The authors declare no conflicts of interest. 7. Spellberg B, Edwards J Jr., Ibrahim A. Novel perspectives
on mucormycosis: Pathophysiology, presentation, and
Author contributions management. Clin Microbiol Rev. 2005;18:556-569.
Conceptualization: Bal Krishna Ojha doi: 10.1128/CMR.18.3.556-569.2005
Investigation: Rajat Verma 8. Singh V, Singh M, Joshi C, Sangwan J. Rhinocerebral
Methodology: Awdhesh Yadav mucormycosis in a patient with type 1 diabetes presenting
Writing-original draft: Rajat Verma as toothache: A case report from Himalayan region of India.
Writing-review & editing: Rajat Verma BMJ Case Rep. 2013;2013:bcr2013200811.
doi: 10.1136/bcr-2013-200811
Ethics approval and consent to participate
9. Sen M, Honavar SG, Bansal R, et al. Epidemiology, clinical
A written informed consent was taken from the patient profile, management, and outcome of COVID-19-associated
before writing the case report. rhino-orbital-cerebral mucormycosis in 2826 patients in
India - Collaborative OPAI-IJO study on Mucormycosis
Consent for publication in COVID-19 (COSMIC), report 1. Indian J Ophthalmol.
An informed consent was taken for publishing the patient 2021;69(7):1670-1692.
data. doi: 10.4103/ijo.IJO_1565_21
Volume 2 Issue 2 (2024) 6 doi: 10.36922/bh.2083

