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Brain & Heart                                                      Step by step 3D ICE guided LAA occlusion




            Table 1. Baseline characteristics                  The patients were scheduled for a follow-up cardiology
                                                               appointment at 6  weeks, which included either cardiac
            Demographics                   TEE and   3D ICE    CTA or TEE. For Group 1, the preferred imaging strategy
                                            3D ICE             at the 6-week follow-up was TEE; however, two patients
                                            (n=7)   (n=13)     underwent cardiac CTA. Meanwhile, for Group 2, cardiac
            Age (years)                     77.4±9.0  73.0±12.1  CTA  was  recommended  at  follow-up  instead  of  TEE;
            Sex, n (%)                                         however, two patients underwent TEE. Follow-up imaging
             Male                           3 (42.9)  10 (76.9)  was either pending or unavailable for two patients (one
             Female                         4 (57.1)  3 (23.1)  from each group).
            Race, n (%)                                        2.1. Procedural steps for LAAO under the guidance
             White                          3 (42.9)  7 (53.8)  of Nuvision 4D ICE probe
             Black or African American      0 (0.0)  5 (38.5)  2.1.1. Insertion into the RA
             Asian                          2 (28.6)  1 (7.7)
             Other                          2 (28.6)  0 (0.0)  a.  Obtain USG-guided common femoral vein access
            Smoking status, n (%)                                 using a micropuncture needle
                                                               b.  Insert a 12F 30-cm Cook sheath into the inferior vena
             Current                        0 (0.0)  0 (0.0)      cava (IVC), ensuring that the 0.035′′ wire remains in
             Former                         4 (57.1)  4 (30.8)    place for facilitating “fluro-map” easy navigation into
             Never                          3 (42.9)  8 (61.5)    the RA (Figure 1A)
             Unknown                        0 (0.0)  1 (7.7)   c.  Advance the ICE probe to the RA by rotating the
            Other risk factors                                    entire probe clockwise or counterclockwise, ensuring
             CHA DS -VASc score             5.1±1.1  4.3±0.9      that the IVC remains visible on top of the image
                 2
                   2
                                                                  throughout the procedure
             HAS-BLED score                 4.7±1.1  4.4±0.9   d.  It may be necessary to apply a slight anterior inclination
             CHF (%)                        2 (28.6)  6 (46.2)    to the deflection knob to remain in the IVC, especially
             Hypertension (%)               6 (85.7)  13 (100)    if entering from the left side and before entering the RA.
             Diabetes mellitus (%)          3 (42.9)  7 (53.8)    This is performed to prevent entering the hepatic veins
             History of stroke/TIA/SE (%)   4 (57.1)  5 (38.5)    and avoid the Eustachian ridge at the IVC/RA junction
             Vascular disease (%)           3 (42.9)  1 (7.7)  e.  Upon reaching the mid-RA (facing the tricuspid valve
             Abnormal renal function (%)    1 (14.3)  5 (38.5)    [TV]), return to the home view.
             Medication usage predisposing to bleeding (%)  6 (85.7)  9 (69.2)  2.1.2. ICE views in mid-RA
             Alcohol (%)                    0 (0.0)  1 (7.7)   a.  The following structures can be visualized by
            Notes: CHA2DS2-VASc is the tool to estimate the annual risk of   performing a gradual clockwise rotation of the probe.
            stroke in atrial fibrillation patients and includes CHF, hypertension,   Alternatively, this can be accomplished by gradually
            age, diabetes mellitus, history of stroke or TIA, vascular disease
            and sex; HAS-BLED is a tool to estimate annual risk of bleeding in   rotating the tip rotation knob
            atrial fibrillation patients taking oral anticoagulants and includes   b.  Home view with the right atrium (RA), TV, and right
            hypertension, abnormal renal/liver function, stroke, bleeding history or   ventricle (RV) in view (Figure 2A)
            predisposition, labile INR, older age (>65 years) and drugs/alcohol use   c.  TV, coronary sinus, pulmonic valve, aortic valve
            concomitantly.                                     d.  Mitral valve (MV), LAA (Figure 2B)
            Abbreviations: TEE: Transesophageal echocardiography;
            3D ICE: Three-dimensional intracardiac echocardiography;   e.  Interatrial septum (IAS)
            TIA: Transient ischemic attack; SE: Systemic thromboembolism.  f.   Left upper and lower pulmonary veins (PVs) (Figure 2C)
                                                               g.  Once past the esophagus and descending aorta, the
            Watchman FLX was used for LAA occlusion in all cases.   right upper and lower PVs can be visualized. It may be
            Notably, four patients in the 3D ICE Group 2 had no pre-  necessary to slightly advance the probe to visualize the
            procedural imaging data available.  Table 2 provides a   upper right PV (Figure 2D)
            summary of the minimalistic approach to LAAO, which is   h.  Return to the neutral home view
            conducted at our center using a 4D Nuvision ICE catheter   2.1.3. ICE views in RV
            (Biosense Webster).
                                                               a.  Lower the probe into the RA
              All patients underwent post-procedural echocardiography   b.  While maintaining the TV in view, apply an anterior
            either the same day or the following day before discharge.   tilt (clockwise rotation of the deflection knob) until


            Volume 2 Issue 4 (2024)                         3                                doi: 10.36922/bh.4018
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