Page 92 - BH-3-3
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Brain & Heart                                                       Combination of EDN and RDN treatment



            medication adjustments are shown in Table 1. Body weight,   postprandial blood glucose, renal function, blood lipids,
            waist  circumference,  24-h  ambulatory  blood  pressure,   liver function, angiotensin, and renal artery CTA were
            heart rate, glycated hemoglobin, fasting blood glucose, 2-h   monitored (Table 2).


            Table 2. Follow‑up results: Changes in blood pressure, blood sugar, and metabolism‑related results
            Test results                        Pre‑operative  1 week after   1 month after   3 months   6 months   1 year after
                                                             surgery   surgery  after surgery  after surgery  surgery
            Physical characteristics
             Weight (kg)                            86         86        85         85        86        86
             BMI (kg/m )                            27.1      27.1       26.8      26.8       27.1     27.1
                     2
             Waist circumference (cm)               93         93        90         90        99        93
            Glycemic index
             HbA1c (%)                              11.0       -          -         9.2       7.0       6.4
             FPG (mmol/L)                           13.3       9.2       8.7        7.7       6.7       6.5
             Breakfast 2hPG (mmol/L)                16.0       7.3       6.9        7.8       7.8       6.9
             Lunch 2hPG (mmol/L)                    20.9       7.9       5.3        8.2       7.7       7.3
             Dinner 2hPG (mmol/L)                   11.2       8.8       8.0        7.7       7.6       6.9
            Clinic blood pressure (mmHg)
             Systolic blood pressure (mmHg)         220        170       154       149        141       135
             Diastolic blood pressure (mmHg)        139        116       112        93        90        80
            24-h ambulatory blood pressure
             24-h average systolic blood pressure (mmHg)  190  170       152       148        135       135
             24-h average diastolic blood pressure (mmHg)  106  100      102        98        84        80
             Average daytime systolic blood pressure (mmHg)  180  165    150       147        130       137
             Average daytime diastolic blood pressure (mmHg)  105  105   102        93        82        86
             Mean nighttime systolic blood pressure (mmHg)  168  155     146       145        130       135
             Mean nocturnal diastolic blood pressure (mmHg)  102  103    103        89        79        84
             24-h average heart rate (beats/min)    98         85        80         74        70        128
            Liver function (IU/L)
             ALT                                    39         37        26         28        33        30
             AST                                    31         23        38         15        19        28
             ALP                                    74         68        59         64        72        84
             GGT                                    43         32        28         27        33.2     27.3
            Blood lipids (mmol/L)
             TG                                     1.50      1.46       1.47      1.74       1.66     1.52
             TC                                     4.21      3.78       3.78      3.85       4.07     3.22
             HDL-C                                  0.88      0.78       0.77      1.33       0.88     0.80
             LDL-C                                  2.82      2.48       2.56      2.42       2.74     2.42
            Kidney function
             BUN (mmol/L)                           5.30      3.70       6.9       6.51       5.19     5.36
             Cr (µmol/L)                            65.0      68.0       70.4      68.3       68.4     59.5
             eGFR (mL/min/1.73m )                  112.4      110.4     108.8      110.2     110.1     115.8
                            2
             Renal artery CTA                      normal      -          -       Normal       -      Normal
            Abbreviations: HbA1c: Glycated hemoglobin; FPG: Fasting blood glucose; 2hPG: 2-h postprandial blood glucose; ALT: Alkaline phosphatase;
            AST: Aspartate aminotransferase; ALP: Alanine aminotransferase GGT; γ-Glutamyl transpeptidase; TG: Triglycerides; TC: Total cholesterol;
            HDL: High density lipoprotein; LDL: Low density lipoprotein; eGFR: Estimated glomerular filtration rate; BMI: Body mass index; BUN: Urea nitrogen;
            Cr: Creatinine; CTA: Computed tomography angiography.


            Volume 3 Issue 3 (2025)                         4                                doi: 10.36922/bh.5123
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