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Brain & Heart Combination of EDN and RDN treatment
medication adjustments are shown in Table 1. Body weight, postprandial blood glucose, renal function, blood lipids,
waist circumference, 24-h ambulatory blood pressure, liver function, angiotensin, and renal artery CTA were
heart rate, glycated hemoglobin, fasting blood glucose, 2-h monitored (Table 2).
Table 2. Follow‑up results: Changes in blood pressure, blood sugar, and metabolism‑related results
Test results Pre‑operative 1 week after 1 month after 3 months 6 months 1 year after
surgery surgery after surgery after surgery surgery
Physical characteristics
Weight (kg) 86 86 85 85 86 86
BMI (kg/m ) 27.1 27.1 26.8 26.8 27.1 27.1
2
Waist circumference (cm) 93 93 90 90 99 93
Glycemic index
HbA1c (%) 11.0 - - 9.2 7.0 6.4
FPG (mmol/L) 13.3 9.2 8.7 7.7 6.7 6.5
Breakfast 2hPG (mmol/L) 16.0 7.3 6.9 7.8 7.8 6.9
Lunch 2hPG (mmol/L) 20.9 7.9 5.3 8.2 7.7 7.3
Dinner 2hPG (mmol/L) 11.2 8.8 8.0 7.7 7.6 6.9
Clinic blood pressure (mmHg)
Systolic blood pressure (mmHg) 220 170 154 149 141 135
Diastolic blood pressure (mmHg) 139 116 112 93 90 80
24-h ambulatory blood pressure
24-h average systolic blood pressure (mmHg) 190 170 152 148 135 135
24-h average diastolic blood pressure (mmHg) 106 100 102 98 84 80
Average daytime systolic blood pressure (mmHg) 180 165 150 147 130 137
Average daytime diastolic blood pressure (mmHg) 105 105 102 93 82 86
Mean nighttime systolic blood pressure (mmHg) 168 155 146 145 130 135
Mean nocturnal diastolic blood pressure (mmHg) 102 103 103 89 79 84
24-h average heart rate (beats/min) 98 85 80 74 70 128
Liver function (IU/L)
ALT 39 37 26 28 33 30
AST 31 23 38 15 19 28
ALP 74 68 59 64 72 84
GGT 43 32 28 27 33.2 27.3
Blood lipids (mmol/L)
TG 1.50 1.46 1.47 1.74 1.66 1.52
TC 4.21 3.78 3.78 3.85 4.07 3.22
HDL-C 0.88 0.78 0.77 1.33 0.88 0.80
LDL-C 2.82 2.48 2.56 2.42 2.74 2.42
Kidney function
BUN (mmol/L) 5.30 3.70 6.9 6.51 5.19 5.36
Cr (µmol/L) 65.0 68.0 70.4 68.3 68.4 59.5
eGFR (mL/min/1.73m ) 112.4 110.4 108.8 110.2 110.1 115.8
2
Renal artery CTA normal - - Normal - Normal
Abbreviations: HbA1c: Glycated hemoglobin; FPG: Fasting blood glucose; 2hPG: 2-h postprandial blood glucose; ALT: Alkaline phosphatase;
AST: Aspartate aminotransferase; ALP: Alanine aminotransferase GGT; γ-Glutamyl transpeptidase; TG: Triglycerides; TC: Total cholesterol;
HDL: High density lipoprotein; LDL: Low density lipoprotein; eGFR: Estimated glomerular filtration rate; BMI: Body mass index; BUN: Urea nitrogen;
Cr: Creatinine; CTA: Computed tomography angiography.
Volume 3 Issue 3 (2025) 4 doi: 10.36922/bh.5123

