Page 216 - EJMO-9-1

Eurasian Journal of Medicine and
Oncology Anticoagulant therapy on parathyroid

Table 3. Parathyroid function recovery time
Postoperative time Anticoagulant group (n = 151) Control group (n = 110) χ 2 P
Post-operative day 3
Number who recovered and proportion (%) 24 (15.89) 16 (14.55) 0.089 0.765
Post-operative day 5
Number who recovered and proportion (%) 45 (29.80) 38 (34.56) 0.660 0.461
Post-operative day 15
Number who recovered and proportion (%) 105 (69.54) 61 (55.45) 5.451 0.0020
Post-operative day 30
Number who recovered and proportion (%) 131 (86.75) 75 (68.18) 13.199 0.00
Post-operative day 90
Number who recovered and proportion (%) 146 (96.69) 100 (90.91) 3.925 0.048
Post-operative day 180
Number who recovered and proportion (%) 151 (100) 106 (96.36) 5.576 0.0018

Table 4. Comparison of PTH indices between the two groups at different post‑operative time points

Groups Post‑operative Post‑operative Post‑operative Post‑operative day
day 3 (pg/mL) day 15 (pg/mL) day 30 (pg/mL) 180 (pg/mL)
Anticoagulant group (n = 151) 10.32 ± 2.23 16.52 ± 3.71 26.98 ± 4.26 33.19 ± 3.89
Control group (n = 110) 11.26 ± 2.37 14.96 ± 3.18 20.38 ± 4.13 26.25 ± 3.88
t −3.275 3.559 12.519 14.248
P 0.001 <0.001 <0.001 <0.001

Table 5. Comparison of serum calcium between the two groups at different post‑operative time points

Groups Post‑operative Post‑operative Post‑operative Post‑operative day
day 3 (mmol/L) day 15 (mmol/L) day 30 (mmol/L) 180 (mmol/L)
Anticoagulant group (n = 151) 2.33 ± 0.15 2.26 ± 0.21 2.49 ± 0.26 2.79 ± 0.34
Control group (n = 110) 2.32 ± 0.19 2.11 ± 0.18 2.20 ± 0.13 2.29 ± 0.37
t 0.320 6.046 10.756 11.302
P 0.750 <0.001 <0.001 <0.001

Table 6. Comparison of treatment efficacy between the two groups
Groups Effective Valid Invalid Total effective rate
Anticoagulant group (n = 151) 65 73 13 137 (91.39)
Control group (n = 110) 33 36 41 69 (62.73)
2 30.001
χ
P <0.001

4. Discussion on recovery status. Most patients with temporary
7,8
parathyroid injury regain function within 6 months
4.1. Incidence of parathyroid dysfunction after total post-operatively. However, definitions of post-operative
9
thyroidectomy parathyroid dysfunction vary across the literature, leading
Hypoparathyroidism is one of the most common to differences in the reported incidences of temporary
complications following total thyroidectomy and can be versus permanent hypoparathyroidism. 10-14 In this study,
classified as either temporary or permanent, depending hypoparathyroidism was defined as a post-operative PTH

Volume 9 Issue 1 (2025) 208 doi: 10.36922/ejmo.8105