Page 114 - EJMO-9-2

Eurasian Journal of
Medicine and Oncology UGVAE of breast lesions

ultimately necessitated lumpectomy. This finding suggests with surgical interventions, providing a cosmetically
that the size of the lesion, as measured through ultrasound, favorable outcome while maintaining clinical efficacy. By
may not be a determining factor in predicting whether offering a reliable and less invasive solution, UGVAE holds
residual tissue remains following the procedure. Similarly, significant potential to redefine the management of benign
the study found no significant association between the breast conditions, particularly in settings where cost and
development of complications, such as hematoma or skin patient comfort are critical considerations.
changes, and the presence of residual lesions, indicating
that complications during or after the procedure are not Acknowledgments
necessarily linked to incomplete excision. These findings The authors sincerely acknowledge the Medical Imaging
contrast with the results of several studies that have Department of King Abdulaziz Medical City, Ministry of
reported a significant correlation between lesion size and the National Guard – Health Affairs, Jeddah, Saudi Arabia,
residual lesions. 30,31,35 Such studies suggest that larger lesion for their valuable support during the data collection
sizes may contribute to incomplete removal, potentially process.
influencing the need for further surgical intervention.
However, it is worth noting that other studies align with Funding
our findings, 32,39 reporting no statistically significant None.
relationship between these variables. This discrepancy
highlights the need for further research to clarify the factors Conflict of interest
influencing residual lesions and the role of procedural
variables in determining clinical outcomes. The authors declare no conflicts of interest related to this
research.
A notable limitation of this study was its relatively small
sample size, which can be attributed to the specific referral Author contributions
protocols in place at our institution. These protocols may Conceptualization: All authors
have restricted the inclusion of a broader and more diverse Data curation: Khalid M. Alshamrani
patient population, potentially affecting the generalizability Formal analysis: Khalid M. Alshamrani
of the findings. Furthermore, the follow-up period for Investigation: Samar Alshehri
this study ranged from 6 to 12 months. While this period Methodology: Khalid M. Alshamrani, Samar Alshehri
is sufficient to observe immediate outcomes and early Resources: Khalid M. Alshamrani, Samar Alshehri, Nesreen
complications, it may not have been long enough to capture Abourokbah
late-onset complications or long-term recurrence rates.
Software: Samar Alshehri
To address these limitations, future research would Supervision: Khalid M. Alshamrani, Samar Alshehri
benefit from larger, multicenter trials that include a more Validation: Nesreen Abourokbah
diverse patient population. Such studies would enhance Visualization: Khalid M. Alshamrani
statistical power and provide a more comprehensive Writing – original draft: All authors
understanding of the procedure’s efficacy and safety. In Writing – review & editing: All authors
addition, extending the follow-up duration in subsequent
studies would allow for the evaluation of long-term Ethics approval and consent to participate
outcomes, including the durability of lesion removal, late Ethical approval for data collection and study conduct was
complications, and overall recurrence rate. These steps obtained from the King Abdullah International Medical
are essential to further validate the findings and establish Research Center Ethics Committee (KAIMRC) (approval
robust evidence supporting the broader clinical application code: RJ20/052/J; approval date: April 26, 2020). KAIMRC
of this procedure. is the research arm of King Saud bin Abdulaziz University

5. Conclusion for Health Sciences and the Ministry of National Guard –
Health Affairs. This study was carried out independently,
UGVAE has emerged as a cost-effective and safe alternative without financial support from public, commercial, or not-
to traditional surgical methods for the removal of benign for-profit funding agencies. In addition, the study adhered
breast lesions. Its minimally invasive nature offers several to the ethical principles outlined in the Declaration of
advantages, including reduced procedural time, minimal Helsinki. Informed consent for participation was not
scarring, and faster recovery, making it a preferred option for required due to the retrospective nature of the study,
both patients and clinicians. Moreover, UGVAE minimizes which involved the use of anonymous archival records.
the physical and psychological burden often associated Data collection was performed using a data collection

Volume 9 Issue 2 (2025) 106 doi: 10.36922/ejmo.8436