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Eurasian Journal of
            Medicine and Oncology                                                      Understanding ulcerative colitis



            scales has been confirmed through extensive research and   rural residential areas, thus providing a comprehensive
            application in various healthcare contexts.        representation across different living conditions.
              The Family Emotional Involvement and Criticism   2.3. Data collection procedure
            Scale (FEICS)-II was also used. Developed by Cleveland
            G. Shields, this self-report tool assesses emotional   A pencil-paper questionnaire was given to the participants.
            involvement  and  criticism  within  familial  relationships,   The study, focusing on LOC, EE, and QOL, was explained
            making it crucial for evaluating EE in family dynamics.   to the participants. They were informed that the purpose of
            FEICS-II demonstrates high reliability (Cronbach’s alpha   the questionnaire was to collect particular data regarding
            > 0.80) and robust concurrent validity (p < 0.001). The   their perceived ability to control influencing factors in
            questionnaire contains  14  belief  statements  related to   their lives and how these factors affect their overall life.
            family experiences, with responses given on a five-point   Before the questionnaire, participants signed an informed
            scale ranging from “Almost Never” to “Almost Always.”   consent form, indicating their voluntary participation.
            The emphasis on the absence of right or wrong answers   They were given a maximum of 45 min to complete the
            fosters an open and supportive research environment.  entire questionnaire and were assured that all data and
                                                               answers gathered would remain confidential. In addition,
              QOL Scale designed by Sarika Sharma and Dr. Nakhat   they were made fully aware of their unrestricted right
            Nasreen was employed in this study. This scale has 42   to refuse participation or withdraw from the study at
            statements (34 positive and 8 negative), scored on a three-  any time, without providing a reason. Only individuals
            point scale. Every question has three responses – “Always,”   diagnosed with UC through colonoscopy and histological
            “Seldom,” “Never.” The scale has a reliability coefficient of 0.80.  standards were included.
            2.2. Participant selection and study criteria        The questionnaire was distributed to 236 participants
            The study encompassed a cohort of 200 Indian participants,   in total, and 208 forms were returned, yielding an 88%
            selected using a purposive sampling technique. The sample   response rate. However, some responses were incomplete
            included 100 UC patients (mild-to-moderate) and 100   and, as a result, excluded in this study. Ultimately, 200
            healthy individuals with no major disease – specifically,   participants’ responses were included in the study,
            non-UC, non-diabetic, and no other major disease   providing comprehensive and useful data.
            related to heart, kidney, gastrointestinal system, brain, or   2.3.1. Demographic details of UC and non-UC
            psychiatric issues. Patients who had undergone surgery   individuals
            for  UC  or  had  severe  UC  were  excluded.  In  addition,
            individuals with major health or psychiatric issues were   Figure 1 shows the demographic features of UC patients.
            excluded. Mild-to-moderate UC was defined as patients   The age group of 40 – 44 years accounted for the largest
            with <4 – 6 bowel movements per day, mild or moderate   proportion (39%), followed by 45 – 49 years (28%), 35 –
            rectal bleeding, and a low overall inflammatory burden.    39 years (21%), and 30 – 34 years (12%). There was an equal
                                                         34
            Each group had an equal number of 50% male and 50%   distribution of males and females. Regarding socioeconomic
            female participants, aged 30 – 50  years. While UC can   status, 22% of participants were from the low-income
            affect individuals at any age, it has peak onset periods   group, 43% from the middle-income group, and 35% from
            between 15 – 30  years and 50 – 70  years.  Therefore,   the  high-income group.  Urban residents  accounted for
                                                 6
            patients with mild-to-moderate symptoms were selected   81%, while 19% lived in rural areas. In terms of education,
            for this age group. After 50 years, factors, such as the aging   56% were graduates, 35% were post-graduates, and 9% were
            process and hormonal changes in women could potentially   undergraduates. Of these patients, 76% were married, 15%
            interfere with the study outcomes.                 were single, and 9% were widowed. In addition, 86% of the
                                                               participants were employed, while 14% were unemployed.
              The patients of mild-to-moderate UC were recruited
            from three hospitals in the Nagpur region, with diagnoses   Figure  2 shows the demographic characteristics of
            confirmed through colonoscopy and tissue biopsy. Disease   non-UC individuals. The majority (36%) were in the
            staging was determined by a gastroenterologist based on   35 – 39 age groups, followed by 45 – 49 years (31%), 30
            signs of inflammation in the colon and other symptoms.   – 34  years (30%), and 40 – 44  years (3%). There was
            All UC patients in this study adhered to a non-spicy, non-  an  equal  distribution  of  males  and  females.  Regarding
            oily, home-prepared diet due to their condition. They were   socioeconomic status, 72% of participants were from the
            also prescribed Mesalazine 1200 (Vegaz OD 1.2  g) and   middle-income group, 12% from the high-income group,
            took it on a regular basis. The participants represented   and 16% from the low-income group. Most participants
            diverse socioeconomic status, from both urban and   (85%) were from urban areas, while few (15%) were from


            Volume 9 Issue 2 (2025)                        111                              doi: 10.36922/ejmo.8596
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