Page 276 - EJMO-9-2
P. 276

Eurasian Journal of
            Medicine and Oncology                                       ANGPTL8 upregulation in CRC with liver metastasis



               by  colorectal  cancer  metastases  requires  YAP-controlled   25.  Zhang R, Abou-Samra AB. A dual role of lipasin (betatrophin)
               plasticity at the micrometastatic stage.  Cancer Res.   in lipid metabolism and glucose homeostasis: consensus and
               2022;82(10):1953-1968.                             controversy. Cardiovasc Diabetol. 2014;13(1):133.
               doi: 10.1158/0008-5472.CAN-21-0933                 doi: 10.1186/s12933-014-0133-8
            15.  Fu  Z,  Berhane  F,  Fite  A,  Seyoum  B,  Abou-Samra  AB,   26.  Abu-Farha M, Cherian P, Qaddoumi MG, et al. Increased
               Zhang R. Elevated circulating lipasin/betatrophin in human   plasma and adipose tissue levels of ANGPTL8/Betatrophin
               type 2 diabetes and obesity. Sci Rep. 2015;4(1):5013.  and ANGPTL4 in people with hypertension. Lipids Health
               doi: 10.1038/srep05013                             Dis. 2018;17(1):35.
            16.  Zhang R. The ANGPTL3-4-8 model, a molecular mechanism      doi: 10.1186/s12944-018-0681-0
               for triglyceride trafficking. Open Biol. 2016;6(4):150272.  27.  Liu  J, Yagi  K, Nohara  A,  et al. High frequency of type  2
               doi: 10.1098/rsob.150272                           diabetes and impaired glucose tolerance in Japanese subjects
                                                                  with the angiopoietin-like protein 8 R59W variant. J Clin
            17.  Gao T, Jin K, Chen P, et al. Circulating betatrophin correlates   Lipidol. 2018;12(2):331-337.
               with triglycerides and postprandial glucose among different
               glucose tolerance statuses-a case-control study. PLoS One.      doi: 10.1016/j.jacl.2017.12.011
               2015;10(8):e0133640.                            28.  Gómez-Ambrosi J, Pascual-Corrales E, Catalán V,  et  al.
               doi: 10.1371/journal.pone.0133640                  Altered concentrations in dyslipidemia evidence a role for
                                                                  ANGPTL8/betatrophin in lipid metabolism in humans.
            18.  Tseng YH, Yeh YH, Chen WJ, Lin KH. Emerging      J Clin Endocrinol Metab. 2016;101(10):3803-3811.
               regulation and function of betatrophin. IJMS. 2014;15(12):
               23640-23657.                                       doi: 10.1210/jc.2016-2084
               doi: 10.3390/ijms151223640                      29.  Ye J, Qin Y, Wang D, Yang L, Yuan G. The relationship between
                                                                  circulating ANGPTL8/betatrophin concentrations and adult
            19.  Sertogullarindan B, Komuroglu AU, Ucler R, Gunbatar H,   obesity: A meta-analysis. Dis Markers. 2019;2019:5096860.
               Sunnetcioglu A, Cokluk E. Betatrophin association with
               serum triglyceride levels in obstructive sleep apnea patients.      doi: 10.1155/2019/5096860
               Ann Thorac Med. 2019;14(1):63-68.               30.  Wu S, Gao H, Ma Y, Fu L, Zhang C, Luo X. Characterisation
               doi: 10.4103/atm.ATM_52_18                         of betatrophin concentrations in childhood and
                                                                  adolescent obesity and insulin resistance. Pediatr Diabetes.
            20.  Xu F, Chen Y, Wang N, Sun K. Bacteria-derived recombinant   2016;17(1):53-60.
               human ANGPTL8/betatrophin  significantly  increases the
               level of triglyceride. Protein J. 2019;38(4):472-478.     doi: 10.1111/pedi.12233
               doi: 10.1007/s10930-019-09825-8                 31.  Guo K, Lu J, Yu H, et al. Serum betatrophin concentrations
                                                                  are significantly increased in overweight but not in obese
            21.  Hassan AB, Salih SF, Hassan II, et al. Circulating betatrophin   or type  2 diabetic individuals.  Obesity (Silver Spring).
               in relation to metabolic, inflammatory parameters, and   2015;23(4):793-797.
               oxidative stress in patients with type  2 diabetes mellitus.
               Diabetes Metab Syndr. 2019;13(1):458-463.          doi: 10.1002/oby.21038
               doi: 10.1016/j.dsx.2018.11.016                  32.  Wang H, Lai Y, Han C, et al. The effects of serum ANGPTL8/
                                                                  betatrophin on the risk of developing the metabolic
            22.  Wang Y, Quagliarini F, Gusarova V,  et al. Mice lacking   syndrome – a prospective study. Sci Rep. 2016;6(1):28431.
               ANGPTL8 (Betatrophin) manifest disrupted triglyceride
               metabolism without impaired glucose homeostasis.  Proc      doi: 10.1038/srep28431
               Natl Acad Sci USA. 2013;110(40):16109-16114.    33.  Chen CC, Susanto H, Chuang WH, Liu TY, Wang CH.
               doi: 10.1073/pnas.1315292110                       Higher serum betatrophin level in type 2 diabetes subjects
                                                                  is associated with urinary albumin excretion and renal
            23.  Fenzl A, Itariu BK, Kosi L,  et  al. Circulating betatrophin   function. Cardiovasc Diabetol. 2016;15:3.
               correlates with atherogenic lipid profiles but not with
               glucose and insulin levels in insulin-resistant individuals.      doi: 10.1186/s12933-015-0326-9
               Diabetologia. 2014;57(6):1204-1208.             34.  Pazgan-Simon M, Zuwala-Jagiello J, Menzyk T, et al. Serum
               doi: 10.1007/s00125-014-3208-x                     betatrophin and irisin levels in hepatocellular carcinoma.
                                                                  J Physiol Pharmacol. 2020;71(1): 113-123.
            24.  Hu H, Sun W, Yu S,  et al. Increased circulating levels of
               betatrophin in newly diagnosed type  2 diabetic  patients.      doi: 10.26402/jpp.2020.1.11
               Diabetes Care. 2014;37:2718-2722.
                                                               35.  Hong BS, Liu J, Zheng J,  et al. Angiopoietin-like protein
               doi: 10.2337/dc14-0602                             8/betatrophin correlates with hepatocellular lipid content


            Volume 9 Issue 2 (2025)                        268                         doi: 10.36922/EJMO025080034
   271   272   273   274   275   276   277   278   279   280   281