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Eurasian Journal of
            Medicine and Oncology                                     Zercepac  + pyrotinib versus pertuzumab in HER2+ BC
                                                                             ®


               positive metastatic breast cancer (PHOEBE): A multicentre,   for patients with human epidermal growth factor receptor
               open-label, randomised, controlled, phase 3 trial.  Lancet   2-positive breast cancer and brain metastases (PERMEATE):
               Oncol. 2021;22(3):351-360.                         A multicentre, single-arm, two-cohort, phase 2 trial. Lancet
               doi: 10.1016/S1470-2045(20)30702-6                 Oncol. 2022;23(3):353-361.
            21.  Yan M, Ouyang Q, Sun T, et al. Pyrotinib plus capecitabine      doi: 10.1016/S1470-2045(21)00716-6









































































            Volume 9 Issue 3 (2025)                        121                         doi: 10.36922/EJMO025100044
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