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Global Health Econ Sustain                                            Global South: Healthier lives with UVC




            Table 1. Performance of UVC LEDs against waterborne pathogens common in the Global South
            Microorganisms              Description           Wavelength   Fluence   Log   %   Sources
                                                                (nm)    (mJ/cm ) reduction reduction
                                                                             2
            Bacteria
             Escherichia coli  Causes gastrointestinal infections and is an   265  8.3 – 10.8  4  99.99  Oguma et al., 2013;
                             indicator of fecal contamination in water                         Song et al., 2019
                                                                 267     12 – 15   4     99.99  Nyangaresi et al.,
                                                                                               2018; 2020
                                                                 275     12 – 15   4     99.99  Nyangaresi et al.,
                                                                                               2020; Pousty et al.,
                                                                                               2021
                                                                 280      13.8     4     99.99  Oguma et al., 2013
             Vibrio cholerae  Causes cholera, a severe diarrheal disease   LP at 254  2.8  4  99.99  Wilson et al., 1992
                             with the potential for outbreaks in areas with   268  60 mW   <3  <99.9  Mariita et al., 2021
                             inadequate sanitation and clean water       and 55 s
             Salmonella spp.  Causes salmonellosis, leading to symptoms like   LP at 254  7.4  4  99.99  Busse et al., 2019
                             diarrhea, fever, and abdominal cramps
             Shigella spp.   Causes shigellosis, a type of dysentery   LP at 254  2.5  4  99.99  Wang et al., 2011
                             characterized by bloody diarrhea and severe
                             abdominal pain.
             Campylobacter jejuni  Causes campylobacteriosis, leading to symptoms   LP at 254  2.1  4  99.99  Butler et al., 1987
                             like diarrhea, fever, and stomach cramps  280  476    4     99.99  Soro et al., 2021
             Burkholderia    Causes melioidosis, which can be contracted from   LP at 254  5.7 – 7.4  4  99.99  Rose & O’Connell,
             pseudomallei    contaminated water or soil in specific regions                    2009
            Viruses
             Rotavirus       A leading cause of severe diarrhea in children,   LP at 254  30  3  99.9  Li et al., 2009
                             especially in areas with poor sanitation and   LP at 254  40  4  99.99  Hu et al., 2012
                             hygiene
             Norovirus       Responsible for outbreaks of gastroenteritis,   LP at 254  27  4  99.99  Lee et al., 2008; Park
                             leading to symptoms like vomiting, diarrhea, and                  et al., 2011
                             stomach cramps                      268      22.5    <3     <99.9  Mariita et al (2022b)

             Adenovirus      Can cause gastroenteritis, respiratory infections,   260  122  4  99.99  Beck et al., 2017
                             and conjunctivitis, and is transmitted through   280  89  4  99.99  Beck et al., 2017
                             contaminated water
                                                                 285      126      3      99.9  Oguma et al., 2016
             Hepatitis A virus   Causes hepatitis A, a viral infection that affects   LP at 254  16  4  99.99  Battigelli et al., 1993
             (HAV)           the liver and is often transmitted through
                             contaminated water or food
                                                                              2
             Hepatitis E virus   Causes hepatitis E, a liver disease often   LP at 254  64.98 (J/m )  1  90  Guerrero-Latorre
             (HEV)           associated with contaminated water in                             et al., 2016
                             developing regions
            Parasites
             Giardia lamblia  Causes giardiasis, leading to symptoms like   LP at 254  20  3  99.9  Campbell & Wallis,
                             diarrhea, abdominal cramps, and nausea                            2002
             Cryptosporidium   Causes cryptosporidiosis, a disease characterized   LP at 254  2.2  3  99.9  Oguma et al., 2001
             parvum          by watery diarrhea that can be severe in   Laser 254 nm  2.8  4  99.99  Beck et al., 2015
                             immunocompromised individuals
            Schistosoma spp.  Causes schistosomiasis (also known as bilharzia),   LP at 254  300  <0.5  -  Hazell et al., 2021
                             a disease transmitted through contaminated   255  300  0.7    -   Hazell et al., 2021
                             freshwater, leading to various symptoms
                             depending on the species involved   265      300     1.5      -   Hazell et al., 2021
                                                                 285      300     0.75     -   Hazell et al., 2021
            Abbreviation: LP: Low pressure.


            Volume 2 Issue 1 (2024)                         8                        https://doi.org/10.36922/ghes.1984
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