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Global Health Econ Sustain                                            Global South: Healthier lives with UVC



            3.2. Potential applications of UVC technology for   cellular repair repression (Martín-Sómer et al., 2023). At the
            waterborne disease prevention in the Global South  265 nm wavelength, UVC LED disinfection can effectively
            Waterborne diseases, such as cholera, typhoid fever, and   inactivate biofilm-bound bacteria such as  Pseudomonas
            diarrheal illnesses, continue to afflict populations worldwide,   aeruginosa (Gora et al., 2019). UVC LEDs emitting in the
            causing significant morbidity and mortality (Smith  et al.,   270 nm range provided effective disinfection of biofilm-
            2014). In tropical regions, where inadequate sanitation   bound cells (Ma et al., 2022).
            and limited access to clean water prevail, these infections   UVC LED technology also effectively disinfects toxic
            threaten the well-being of millions (Prüss-Ustün et al., 2019).   and carcinogenic contaminants often caused by synthetic
            Improving access to drinking water, sanitation facilities, and   dyes found in wastewater (Ahmadi & Ghanbari, 2018).
            hygiene practices is critical for improving public health in   Other studies have found that when combined with
            lower-resourced regions, such as the Global South, where   dissolved organic matter microfiltration, UVC LED is also
            diarrheal diseases are major contributors to morbidity and   highly effective, with a 6 – 7 log reduction in Giardia sp. and
            mortality (Manetu & Karanja, 2021).                Cryptosporidium sp. (Lee et al., 2023). UVC LED irradiation
              Traditional water treatment methods have limitations   was found to be effective at treating municipal wastewater
            in effectively eliminating pathogenic microorganisms,   for the disinfection of microbes, including E. coli and the
            necessitating  the exploration  of novel  approaches. Past   SARS-Cov-2 virus (Yu et al., 2023). Another study found
            studies have shown that point-of-use water disinfection   that UVC LED effectively inactivated pathogenic bacteria
            through conventional methods such as chlorination was   Aeromonas salmonicida and  Escherichia coli  (4.5 log
            effective at preventing diarrheal diseases in high-risk rural   inactivation) and that avoidance of visible light spectrums
            Kenyan regions and other Global South countries such as   inhibited bacterial reactivation (Zhang  et al., 2023).
            Bolivia and Bangladesh (Arnold & Colford, 2007; Garrett et   UVC LED irradiation was also effective at disinfecting
            al., 2008; Sobsey et al., 2003). With evidence that point-of-use   human noroviruses found in wastewater systems and has
            chemical water treatment effectively reduces transmission of   positive implications for protecting natural water sources
            waterborne pathogens, it stands to reason that improvements   from  contaminated  wastewater  runoff  (Mariita  et al.,
            to the disinfection process would only positively impact these   2022a). Comparable studies also found the simultaneous
            communities. UVC LED technology emerges as a promising   disinfection and organic microcontaminant elimination by
            solution, potentially enhancing life quality, public health, and   UVC-LED-Driven Advanced Oxidation Processes effective
            economic outcomes (Martín-Sómer et al., 2023).     and crucial for scaling tertiary wastewater treatment
              UVC LED technology holds immense potential to improve   (Miralles-Cuevas et al., 2021). There is also evidence that
            life quality and public health outcomes by reducing the   UVC LED + impeller systems effectively inactivate human
            incidence of waterborne diseases. Studies have demonstrated   norovirus in brine water, which is impactful for certain
            the efficacy of UVC LED systems in inactivating a wide range   food manufacturing industries (Yoon et al., 2022).
            of waterborne pathogens, including bacteria, viruses, and   UVC LED technology is also effective on smaller-scale
            protozoa (Beck et al., 2017; Nyangaresi et al., 2019; Shen et al.,   water disinfection systems, such as single-unit disinfection
            2020; Song et al., 2016). In 2020, 5.8 billion people, or 74% of   within personal water bottles.  The purgaty One system
            the global population, used a safely managed drinking water   (cap+bottle) is a stainless-steel water bottle with UVC
            service on-site. By incorporating UVC LED technology into   LED disinfection capabilities housed within the bottle
            water treatment processes, the risk of waterborne infections   cap, which was found to be greater than 99% effective
            can be significantly reduced, leading to improved health   at the inactivation of  E. coli, P. aeruginosa, V. cholerae,
            outcomes and enhanced well-being for affected communities.   and heterotrophic contaminants (Mariita  et al., 2021).
            UVC LED water purification could dramatically increase the   In addition to drinking water disinfection, point-of-use
            number of people, particularly those in the Global South, with   UVC LED technology in showerheads effectively treats
            consistent access to a safely managed drinking water service   household bathing water (Cates & Torkzadeh, 2020).
            in households, healthcare facilities, and schools.
                                                               3.3.2. Comparative analysis with alternative water
            3.3. Effectiveness of UVC LED technology in        treatment methods
            waterborne disease prevention
                                                               Water purification using mercury lamps was first performed
            3.3.1. Research studies and evidence supporting the   in the early 20  century and saw large-scale implementation
                                                                          th
            efficacy of UVC LED technology                     in the 1950s. However, using mercury lamps for water
            Studies have shown that 265 nm wavelengths have higher   disinfection requires heavy energy expenditures, hazardous
            germicidal effects, while 280 nm wavelengths have better   materials, and bulky systems  (Gora  et al., 2019). In


            Volume 2 Issue 1 (2024)                         9                        https://doi.org/10.36922/ghes.1984
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