Page 24 - GHES-3-3

Global Health Economics and
Sustainability
Sustainable therapeutic Artemisia

development. Nature Reviews Microbiology, 12(5):355-367. How does COVID-19 affect the heart? Current Cardiology
Reports, 25(3):171-184.
https://doi.org/10.1038/nrmicro3240
https://doi.org/10.1007/s11886-023-01841-6
Palacios-Lopez, A., Christiaensen, L., & Kilic, T. (2017). How
much of the labor in African agriculture is provided by Singh, S.J., Baldwin, M.M., Daynes, E., Evans, R.A., Greening, N.J.,
women? Food Policy, 67:52-63. Jenkins, R.G., et al. (2023). Respiratory sequelae of
COVID-19: pulmonary and extrapulmonary origins, and
https://doi.org/10.1016/j.foodpol.2016.09.017
approaches to clinical care and rehabilitation. The Lancet
Parveen, S. (2021). In silico drug repurposing of fda-approved Respiratory Medicine, 11(8):709-725.
artemisinins as potent chemotherapeutics targeting BCL-2, https://doi.org/10.1016/S2213-2600(23)00159-5
CDK-6 and VEGFR-2: Density functional exploration and
molecular docking study. Biointerface Research in Applied Snider, D., & Weathers, P.J. (2021). In vitro reduction of
Chemistry, 11:9604-9618. Plasmodium falciparum gametocytes: Artemisia spp. tea
infusions vs. artemisinin. Journal of Ethnopharmacology,
Peplow, M. (2013). Malaria drug made in yeast causes market 268:113638.
ferment. Nature, 494(7436):160-161.
Staub, S.A. (2023). Malaria Business: Knowledge, Power and
https://doi.org/10.1038/494160a the Governance of Artemisia in the Fight Against Malaria.
Peplow, M. (2016). Synthetic malaria drug meets market Gainesville, FL: University of Florida.
resistance: First commercial deployment of synthetic biology Stebbings, S., Beattie, E., McNamara, D., & Hunt, S. (2016). A pilot
for medicine has modest impact. Nature, 530(7591):389-391. randomized, placebo-controlled clinical trial to investigate
https://doi.org/10.1038/530390a the efficacy and safety of an extract of Artemisia annua
administered over 12 weeks, for managing pain, stiffness,
Räth, K., Taxis, K., Walz, G., Gleiter, C.H., Li, S.M., & Heide, L. and functional limitation associated with osteoarthritis of
(2004). Pharmacokinetic study of artemisinin after oral the hip and knee. Clinical Rheumatology, 35(7):1829-1836.
intake of a traditional preparation of Artemisia annua L.
(annual wormwood). The American Journal of Tropical https://doi.org/10.1007/s10067-015-3110-z
Medicine and Hygiene, 70(2):128-132. Supaibulwattana, K., Kuntawunginn, W., Cha-Um, S., &
https://doi.org/10.4269/ajtmh.2004.70.128 Kirdmanee, C. (2011). Artemisinin accumulation
and enhanced net photosynthetic rate in Qinghao
Rijken, M.J., McGready, R., Phyo, A.P., Lindegardh, N., (Artemisia annua L.) Hardened in vitro in Enriched-CO
Tarning, J., Laochan, N., et al. (2011). Pharmacokinetics photoautotrophic conditions. Plant Omics, 4(2):75-81. 2
of dihydroartemisinin and piperaquine in pregnant and
nonpregnant women with uncomplicated falciparum Taljaard, L., Probst, A., Tornow, R., Keiser, J., Haynes, R.K., &
malaria. Antimicrobial Agents and Chemotherapy, Van der Kooy, F. (2022). In vitro antischistosomal activity of
55(12):5500-5506. Artemisia annua and Artemisia afra extracts. Phytomedicine
Plus, 2(3):100279.
https://doi.org/10.1128/AAC.05067-11
https://doi.org/10.1016/j.phyplu.2022.100279
Risite, H., Salim, M.H., Oudinot, B.T., Ablouh, E.H., Joyeux, H.T.,
Sehaqui, H., et al. (2022). Artemisia annua stems a new Thu, B.T.T., Van Minh, T., Lim, B.P., & Keng, C.L. (2011). Effects
sustainable source for cellulosic materials: Production and of environmental factors on growth and artemisinin content
characterization of cellulose microfibers and nanocrystals. of Artemisia annua L. Tropical Life Sciences Research,
Waste and Biomass Valorization, 13(4):2411-2423. 22(2):37-43.
https://doi.org/10.1007/s12649-021-01658-w Titulaer, H., Zuidema, J., Kager, P., Wetsteyn, J., Lugt, C.B., &
Merkus, F. (1990). The pharmacokinetics of artemisinin after
Romero, M.R., Efferth, T., Serrano, M.A., Castaño, B., Macias, R.I., oral, intramuscular and rectal administration to volunteers.
Briz, O., et al. (2005). Effect of artemisinin/artesunate as Journal of pharmacy and Pharmacology, 42(11):810-813.
inhibitors of hepatitis B virus production in an “in vitro”
replicative system. Antiviral Research, 68(2):75-83. https://doi.org/10.1111/j.2042-7158.1990.tb07030.x
Triemer, S., Gilmore, K., Vu, G.T., Seeberger, P.H., & Seidel‐
https://doi.org/10.1016/j.antiviral.2005.07.005
Morgenstern, A. (2018). Literally green chemical synthesis
Savage, R.L., Hill, G.R., Barnes, J., Kenyon, S.H., & Tatley, M.V. of artemisinin from plant extracts. Angewandte Chemie
(2019). Suspected hepatotoxicity with a supercritical carbon International Edition English, 57(19):5525-5528.
dioxide extract of Artemisia annua in grapeseed oil used in
New Zealand. Frontiers in Pharmacology, 10:1448. https://doi.org/10.1002/anie.201801424
Tu, Y. (2016). Artemisinin-a gift from traditional Chinese
https://doi.org/10.3389/fphar.2019.01448
medicine to the world (Nobel lecture). Angewandte Chemie
Sewanan, L.R., Clerkin, K.J., Tucker, N.R., & Tsai, E.J. (2023). International Edition, 55(35):10210-10226.

Volume 3 Issue 3 (2025) 16 https://doi.org/10.36922/ghes.4927