Page 25 - GHES-3-3

Global Health Economics and
Sustainability
Sustainable therapeutic Artemisia

https://doi.org/10.1002/anie.201601967 Simulated digestion of dried leaves of Artemisia annua
consumed as a treatment (pACT) for malaria. Journal of
Wang, D., Shi, C., Alamgir, K., Kwon, S., Pan, L., Zhu, Y.,
et al. (2022). Global assessment of the distribution and Ethnopharmacology, 151(2):858-863.
conservation status of a key medicinal plant (Artemisia https://doi.org/10.1016/j.jep.2013.11.043
annua L.): The roles of climate and anthropogenic activities. Wetzstein, H.Y., Porter, J.A., Janick, J., Ferreira, J.F.S., &
Science of the Total Environment, 821:153378.
Mutui, T.M. (2018). Selection and clonal propagation of
https://doi.org/10.1016/j.scitotenv.2022.153378 high artemisinin genotypes of Artemisia annua. Frontiers in
Plant Science, 9:358.
Weathers, P., Desrosiers, M., & Cornet-Vernet, L. (2024). Artemisia
annua, a cost-effective sustainable therapeutic for the https://doi.org/10.3389/fpls.2018.00358
masses and the political challenges for its implementation. White, N.J. (2008). Qinghaosu (artemisinin): The price of success.
In: Krueger, R., Telliel, Y., & Soboyejo, W., editors. Science, Science, 320(5874):330-334.
Engineering, and Sustainable Development: Cases in
Planning, Health, Agriculture, and the Environment. https://doi.org/10.1126/science.1155165
Germany: De Gruyter. p21-36. WHO. (2013). WHO Traditional Medicine Strategy:
Weathers, P., Towler, M., Kiani, B.H., Dolivo, D., & Dominko, T. 2014-2023. Available from: https://iris.who.int/
(2024). Differential anti-fibrotic and remodeling responses bitstream/handle/10665/92455/9789241506090_eng.
of human dermal fibroblasts to Artemisia sp., artemisinin, pdf;jsessionid=0bb134e5ee8a8ed49f6a35bdb9a5c9f1 [Last
and its derivatives. Molecules, 29(9):2107. accessed on 2024 Jul 31].
https://doi.org/10.3390/molecules29092107 World Health Organization. (2002). WHO Traditional Medicine
Strategy 2002-2005. World Health Organization; Retrieved
Weathers, P.J. (2023). Artemisinin as a therapeutic vs. its more May 13, 2024. Available from: https://www.who.int/
complex Artemisia source material. Natural Product Reports, publications/i/item/who-edm-trm-2002.1 [Last accessed on
40(7):1158-1169.
2024 May 13]
Weathers, P.J., & Towler, M.J. (2014). Changes in key constituents Zheng, H., Williams, J.T., Aleiwi, B., Ellsworth, E., &
of clonally propagated Artemisia annua L. during preparation Abramovitch, R.B. (2019). Inhibiting Mycobacterium
of compressed leaf tablets for possible therapeutic use. tuberculosis DosRST signaling by targeting response
Industrial Crops and Products, 62:173-178.
regulator DNA binding and sensor kinase heme. ACS
https://doi.org/10.1016/j.indcrop.2014.08.033 Chemical Biology, 15(1):52-62.
Weathers, P.J., Arsenault, P.R., Covello, P.S., McMickle, A., https://doi.org/10.1021/acschembio.8b00849
Teoh, K.H., & Reed, D.W. (2011). Artemisinin production Zhou, Y., Gilmore, K., Ramirez, S., Settels, E., Gammeltoft, K. A.,
in Artemisia annua: Studies in planta and results of a novel Pham, L.V., et al. (2021). In vitro efficacy of artemisinin-
delivery method for treating malaria and other neglected based treatments against SARS-CoV-2. Scientific Reports,
diseases. Phytochemistry Reviews, 10(2):173-183.
11(1):1-14.
https://doi.org/10.1007/s11101-010-9166-0
https://doi.org/10.1038/s41598-021-93361-y
Weathers, P.J., Elfawal, M.A., Towler, M.J., Acquaah-Mensah, G.K., Zime-Diawara, H., De Tove, Y.S.S., Akogbeto, O.E., Ogouyemi-
& Rich, S.M. (2014). Pharmacokinetics of artemisinin Hounto, A., Gbaguidi, F.A., Kinde-Gazard, D., et al. (2015).
delivered by oral consumption of Artemisia annua dried Etude de l’efficacité et de la tolérance d’une tisane à base de
leaves in healthy vs. Plasmodium chabaudi-infected mice. Artemisia annua L.(Asteraceae) cultivée au Bénin pour la
Journal of Ethnopharmacology, 153(3):732-736.
prise en charge du paludisme simple. International Journal
https://doi.org/10.1016/j.jep.2014.03.037 of Biological and Chemical Sciences, 9(2):692-702.
Weathers, P.J., Jordan, N.J., Lasin, P., & Towler, M.J. (2014). https://doi.org/10.4314/ijbcs.v9i2.10

Volume 3 Issue 3 (2025) 17 https://doi.org/10.36922/ghes.4927