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Gene & Protein in Disease Photothermal therapy of pentamethine cyanine
A
B C D
E F G H
I J K L M
N
O P Q R S
Figure 3. The biodistribution, tumor inhibition and side effects of CY5-664 in vivo. (A) The fluorescence imaging at different times after injection of
CY5-664. (B) The fluorescence imaging of main organs and tumor at 24 h after injection. (C) The change of tumor volume during the observation
period. (D) Photos of the tumor after treatment. (E) Tumor quality after treatment. (F–H) The morphological characteristics of tumor tissue, NS + Laser
(F), CY5-664 (G), and CY5-664 + Laser (H). (I) The change of body weight during the observation period. (J) The change of ALT in the liver. (K) The
change of AST in the liver. (L) The change of Cre in the kidney. (M) The change of BUN in the kidney. (N) The morphological characteristics of main organs
with or without CY5-664 treatment. (O–S) The change of main organs. *P < 0.05; **P < 0.01; ***P < 0.001.
Volume 1 Issue 1 (2022) 7 https://doi.org/10.36922/gpd.v1i1.87
