Page 42 - GPD-1-1
P. 42

Gene & Protein in Disease                                 Genetically engineered T cells in cancer immunotherapy



               management. Blood Rev, 34: 45–55.               41.  Huarte E, O’Connor RS, Peel MT,  et al., 2020, Itacitinib
                                                                  (INCB039110),  a  JAK1  inhibitor,  reduces  cytokines
               https://doi.org/10.1016/j.blre.2018.11.002
                                                                  associated with cytokine release syndrome induced by CAR
            31.  Maude SL, Frey N, Shaw PA, et al., 2014, Chimeric antigen   T-cell therapy. Clin Cancer Res, 26(23): 6299–6309.
               receptor T cells for sustained remissions in leukemia. N Engl
               J Med, 371(16): 1507–1517.                         https://doi.org/10.1158 / 1078-0432.CCR-20-1739
               https://doi.org/10.1056/NEJMoa1407222           42.  Casucci M, Falcone L, Camisa B, et al., 2018, Extracellular
                                                                  NGFR spacers allow efficient tracking and enrichment of
            32.  Gust J, Hay KA, Hanafi LA, et al., 2017, Endothelial activation   fully functional CAR-T cells co-expressing a suicide gene.
               and blood-brain barrier disruption in neurotoxicity after   Front Immunol, 9: 507.
               adoptive immunotherapy with CD19 CAR-T cells. Cancer
               Discov, 7(12): 1404–1419.                          https://doi.org/10.3389/fimmu.2018.00507
               https://doi.org/10.1158 / 2159-8290.CD-17-0698  43.  Ying Z, Huang XF, Xiang X, et al., 2019, A safe and potent
                                                                  anti-CD19 CAR T cell therapy. Nat Med, 25(6): 947–953.
            33.  Giavridis T, van der Stegen SJ, Eyquem J, et al., 2018, CAR
               T cell-induced cytokine release syndrome is mediated by      https://doi.org/10.1038/s41591-019-0421-7
               macrophages and abated by IL-1 blockade. Nat Med, 24(6):   44.  Brudno  JN,  Lam  N,  Vanasse  D,  et al.,  2020,  Safety  and
               731–738.                                           feasibility of anti-CD19 CAR T cells with fully human
               https://doi.org/10.1038/s41591-018-0041-7          binding  domains  in  patients  with  B-cell  lymphoma.  Nat
                                                                  Med, 26(2): 270–280.
            34.  Fischer JW, Bhattarai N, 2021, CAR-T cell therapy:
               Mechanism, management, and mitigation of inflammatory      https://doi.org/10.1038/s41591-019-0737-3
               toxicities. Front Immunol, 12: 693016.          45.  Fraietta JA, Lacey SF, Orlando EJ, et al., 2018, Determinants
               https://doi.org/10.3389/fimmu.2021.693016          of response and resistance to CD19 chimeric antigen
                                                                  receptor (CAR) T cell therapy of chronic lymphocytic
            35.  Chen X, Li X, Liu Y, et al., 2020, A phase I clinical trial of   leukemia. Nat Med, 24(5): 563–571.
               chimeric antigen receptor-modified T cells in patients with
               relapsed and refractory lymphoma. Immunotherapy, 12(10):      https://doi.org/10.1038/s41591-018-0010-1
               681–696.
                                                               46.  Deng Q, Han G, Puebla-Osorio N, et al., 2020, Characteristics
               https://doi.org/10.2217/imt-2020-0022              of anti-CD19 CAR T cell infusion products associated with
                                                                  efficacy and toxicity in patients with large B cell lymphomas.
            36.  Norelli M, Camisa B, Barbiera G, et al., 2018, Monocyte-
               derived IL-1 and IL-6 are differentially required for   Nat Med, 26(12): 1878–1887.
               cytokine-release syndrome and neurotoxicity due to CAR T      https://doi.org/10.1038/s41591-020-1061-7
               cells. Nat Med, 24(6): 739–748.
                                                               47.  Wang X, Brea LT, Yu J, 2019, Immune modulatory functions
               https://doi.org/10.1038/s41591-018-0036-4          of EZH2 in the tumor microenvironment: Implications in
            37.  Staedtke V, Bai RY, Kim K, et al., 2018, Disruption of a self-  cancer immunotherapy. Am J Clin Exp Urol, 7(2): 85–91.
               amplifying catecholamine loop reduces cytokine release   48.  John LB,  Devaud C,  Duong CP,  et al., 2013,  Anti-PD-1
               syndrome. Nature, 564(7735): 273–277.              antibody therapy potently enhances the eradication of
               https://doi.org/10.1038/s41586-018-0774-y          established tumors by gene-modified T cells.  Clin Cancer
                                                                  Res, 19(20): 5636–5646.
            38.  Liu Y, Fang Y, Chen X, et al., 2020, Gasdermin E-mediated
               target cell pyroptosis by CAR T cells triggers cytokine release      https://doi.org/10.1158 / 1078-0432.CCR-13-0458
               syndrome. Sci Immunol, 5(43): eaax7969.         49.  Choi BD, Yu X, Castano AP,  et al., 2019, CRISPR-Cas9
               https://doi.org/10.1126/sciimmunol.aax7969         disruption of PD-1 enhances activity of universal EGFRvIII
                                                                  CAR T cells in a preclinical model of human glioblastoma.
            39.  Liu Y, Chen X, Wang D,  et al., 2018, Hemofiltration   J Immunother Cancer, 7(1): 304.
               successfully eliminates severe cytokine release syndrome
               following CD19 CAR-T-cell therapy. J Immunother, 41(9):      https://doi.org/10.1186/s40425-019-0806-7
               406–410.                                        50.  Chong EA, Alanio C, Svoboda J,  et al., 2022,
               https://doi.org/10.1097/CJI.0000000000000243       Pembrolizumab for B-cell lymphomas relapsing after or
                                                                  refractory to CD19-directed CAR T-cell  therapy.  Blood,
            40.  Xiao X, He X, Li Q, et al., 2019, Plasma exchange can be an   139(7): 1026–1038.
               alternative therapeutic modality for severe cytokine release
               syndrome after chimeric antigen receptor-T cell infusion:      https://doi.org/10.1182/blood.2021012634
               A case report. Clin Cancer Res, 25(1): 29–34.
                                                               51.  Liu M, Wang X, Li Z,  et al., 2020, Synergistic effect of
               https://doi.org/10.1158 / 1078-0432.CCR-18-1379    ibrutinib and CD19 CAR-T cells on Raji cells in vivo and


            Volume 1 Issue 1 (2022)                         11                     https://doi.org/10.36922/gpd.v1i1.114
   37   38   39   40   41   42   43   44   45   46   47