Page 129 - GPD-3-3

Gene & Protein in Disease Hydrogen sulfide ameliorates NAFLD

and nonalcoholic fatty liver disease in mice. Life Sci. 34. Huang D, Jing G, Zhu S. Regulation of mitochondrial
2020;252:117661. respiration by hydrogen sulfide. Antioxidants (Basel).
2023;12(8):1644.
doi: 10.1016/j.lfs.2020.117661
doi: 10.3390/antiox12081644
24. Bełtowski J. Synthesis, metabolism, and signaling
mechanisms of hydrogen sulfide: An overview. Methods Mol 35. Ngowi EE, Sarfraz M, Afzal A, et al. Roles of hydrogen
Biol. 2019;2007:1-8. sulfide donors in common kidney diseases. Front Pharmacol.
2020;11:564281.
doi: 10.1007/978-1-4939-9528-8_1
doi: 10.3389/fphar.2020.564281
25. Liu Y, Li J, Chen H, et al. Magnet-activatable nanoliposomes
as intracellular bubble microreactors to enhance drug 36. Lian CY, Zhai ZZ, Li ZF, Wang L. High fat diet-triggered
delivery efficacy and burst cancer cells. Nanoscale. non-alcoholic fatty liver disease: A review of proposed
2019;11(40):18854-18865. mechanisms. Chem Biol Interact. 2020;330:109199.
doi: 10.1039/c9nr07021d doi: 10.1016/j.cbi.2020.109199
26. Larraufie P, Haroun K, Fleury C, Andriamihaja M, 37. Wang H, Zhu YY, Wang L, et al. Mangiferin ameliorates
Blachier F. Regulation of enteroendocrine cell respiration by fatty liver via modulation of autophagy and inflammation
the microbial metabolite hydrogen sulfide. Front Endocrinol. in high-fat-diet induced mice. Biomed Pharmacother.
2023;14:1123364. 2017;96:328-335.
doi: 10.3389/fendo.2023.1123364 doi: 10.1016/j.biopha.2017.10.022
27. Brown EM, Bowden NB. Stabilities of three key biological 38. Van Rooyen DM, Larter CZ, Haigh WG, et al. Hepatic
trisulfides with implications for their roles in the release free cholesterol accumulates in obese, diabetic mice and
of hydrogen sulfide and bioaccumulation of sulfane sulfur. causes nonalcoholic steatohepatitis. Gastroenterology.
ACS Omega. 2022;7(13):11440-11451. 2011;141:1393-1403, 1403.e1-5

doi: 10.1021/acsomega.2c00736 doi: 10.1053/j.gastro.2011.06.040
28. Ubuka T. Assay methods and biological roles of labile sulfur 39. Kannt A, Madsen AN, Kammermeier C, et al. Incretin
in animal tissues. J Chromatogr B Analyt Technol Biomed Life combination therapy for the treatment of non‐alcoholic
Sci. 2002;781(1-2):227-249. steatohepatitis. Diabetes Obes Metab. 2020;22(8):1328-1338.

doi: 10.1016/s1570-0232(02)00623-2 doi: 10.1111/dom.14035
29. Wilkie SE, Borland G, Carter RN, Morton NM, Selman C. 40. Wu D, Zheng N, Qi K, et al. Exogenous hydrogen sulfide
Hydrogen sulfide in ageing, longevity and disease. Biochem mitigates the fatty liver in obese mice through improving
J. 2021;478(19):3485-3504. lipid metabolism and antioxidant potential. Med Gas Res.
2015;5:1.
doi: 10.1042/bcj20210517
doi: 10.1186/s13618-014-0022-y
30. Meng GL, Wang J, Xiao YJ, et al. GYY4137 protects against
myocardial ischemia and reperfusion injury by attenuating 41. Larter CZ, Yeh MM, Van Rooyen DM, et al. Roles of adipose
oxidative stress and apoptosis in rats. J Biomed Res. restriction and metabolic factors in progression of steatosis
2015;29(3):203-213. to steatohepatitis in obese, diabetic mice. Gastroenterol
Hepatol. 2009;24:1658-1668.
doi: 10.7555/jbr.28.20140037
doi: 10.1111/j.1440-1746.2009.05996.x
31. Chen JJ, Van Der Vlies AJ, Hasegawa U. Hydrogen sulfide-
releasing micelles for promoting angiogenesis. Polym Chem. 42. Heeren J, Scheja L. Metabolic-associated fatty liver disease
2020;11(27):4454-4463. and lipoprotein metabolism. Mol Metab. 2021;50:101238.
doi: 10.1039/d0py00495b doi: 10.1016/j.molmet.2021.101238
32. Kumar M, Sandhir R. Hydrogen sulfide in physiological and 43. Elnegaard JJ, Iena FM, Herold J, Lebeck J. Sex‐specific effect of
pathological mechanisms in brain. CNS Neurol Disord Drug AQP9 deficiency on hepatic triglyceride metabolism in mice
Targets. 2018;17(9):654-670. with diet‐induced obesity. J Physiol. 2023;602:3131-3149.
doi: 10.2174/1871527317666180605072018 doi: 10.1113/jp284188
33. Gao W, Liu YF, Zhang YX, et al. The potential role of 44. Zhang L, Zhang Z, Li C, et al. S100A11 promotes liver
hydrogen sulfide in cancer cell apoptosis. Cell Death Discov. steatosis via FOXO1-mediated autophagy and lipogenesis.
2024;10(1):114. Cell Mol Gastroenterol Hepatol. 2021;11(3):697-724.
doi: 10.1038/s41420-024-01868-w doi: 10.1016/j.jcmgh.2020.10.006

Volume 3 Issue 3 (2024) 11 doi: 10.36922/gpd.3409