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Global Translational Medicine Stem cells in aortic aneurysm

Table 1. (Continued)
Species Diseases Number of Gender and Age (SD) Induction method Cell type Marker References
samples genotype
EC Cdh5, Pecam1, Fabp4
SMC Myh11, Acta2, Tagln
T cell Cd3d, Cd3g, Cd28
B cell Cd79a, Cd79b, Ly6d
DC Cd209a, Cd74
Granulocyte S100a8, Ccr1, Ly6g
Mus MFS 4 Fbn1 C1041G/+ and 2 males and 4 weeks/24 Fbn1 C1041G/+ mouse SMC Acta2, Myl9, Myh11, [32]
musculus 3 controls 2 females weeks MFS model Tpm2, Tagln
Fbn1 C1041G/+ Modulated Fn1, Mgp, Nupr1, Eln,
and 2 males SMC Tnfrsf11b, Igfbp2
and 1 female
controls Fibro 1 Hsd11b1, Dpep1,
Cygb, Gdf10, Smoc2
Fibro 2 1500015O10Rik, Prg4,
Comp, Wif1, Thbs1
Ly6a+Fibro Pi16, Ly6a, Clec3b,
C3, Mfap5
EC Pecam1, Cldn5,
Ctla2a, Nts, Ccl21a
Macro Lyz2, Ccl4, C1qb,
Cxcl2, Cd74
Pericardial Upk3b, Msln, Myl7,
Igfbp6, Igfbp5
Mus TAAD BAPN-induced Male 3-week-old BAPN-induced SMC Myh11, Cnn1 [44]
musculus TAAD and C57BL/6J mice induced mouse model Fibro Pdgfra, Lum
control, 3/group with BAPN for
28 days EC Cdh5, Tie1
T cell Cd3d, Cd3g
B cell Cd79a, Cd19
Macro Itgam, Cd14
Mus AAD WT and Male and 4-week-old Ang II-infusion SMC Acta2, Myh11, Mylk [45]
musculus Sting-deficient female WT mice with HFD mouse model
mice unchallenged C57BL/6J and for 5 weeks Macro Cd68, Adger1, F13a1
or challenged with Sting-deficient
HFD/Ang II, 3/ mice Fibro NA
group
EC NA

Homo ATAA 8 patients, 4 males and 67.6 (8.1) years / T cell Ccl5, Trbc2, Cd2, [46]
sapiens 3 controls 4 females in in patients and Cd3d, Trac, Cd52,
patients and 62 (1) years in Cxcr4, Il32, Gzmk,
1 male and controls Il7r
2 females in Mono Cxcl8, Il1b, Hla-dra,
controls C1qa, C1qb, Cxcl3,
Hla-dpa1, Cxcl2,
C1qc, Cd74, Selenop
SMC1 Acta1, Myl9, Tagln,
Tpm2, Cald1, Myh11,
Dstn, Pln, Mfge8
NK Xcl1, Xcl2, Klrd1,
Gnly, Klrc1, Cd7,
(Cont’d...)

Volume 2 Issue 1 (2023) 6 https://doi.org/10.36922/gtm.v2i1.241