Page 35 - GTM-3-2
P. 35
Global Translational Medicine Impact of flavonoids on vascular health
2. Kumar S, Pandey AK. Chemistry and biological activities 14. Juliana C, Paula A, Erica A, Mario H, Alexandra C, Maria C.
of flavonoids: An overview. ScientificWorldJournal. Flavonoid contents and antioxidant activity in fruit, vegetables
2013;2013:162750. and other types of food. Agric Sci. 2015;6(4):426-435.
doi: 10.1155/2013/162750 doi: 10.4236/as.2015.64042
3. Jiang B, Song J, Jin Y. A flavonoid monomer tricin in gramineous 15. Atrahimovich D, Avni D, Khatib S. Flavonoids-
plants: Metabolism, bio/chemosynthesis, biological properties, macromolecules interactions in human diseases with focus
and toxicology. Food Chem. 2020;320:126617. on Alzheimer, Atherosclerosis and Cancer. Antioxidants
(Basel). 2021;10(3):423.
doi: 10.1016/j.foodchem.2020.126617
doi: 10.3390/antiox10030423
4. Guven H, Arici A, Simsek O. Flavonoids in our foods:
A short review. J Basic Clin Health Sci. 2019;3(2):96-106. 16. Tungmunnithum D, Thongboonyou A, Pholboon A,
Yangsabai A. Flavonoids and other phenolic compounds
doi: 10.30621/jbachs.2019.555
from medicinal plants for pharmaceutical and medical
5. Nabavi SM, Šamec D, Tomczyk M, et al. Flavonoid aspects: An overview. Medicines (Basel). 2018;5(3):93.
biosynthetic pathways in plants: Versatile targets for
metabolic engineering. Biotechnol Adv. 2020;38:107316. doi: 10.3390/medicines5030093
17. Shukla R, Pandey V, Vadnere GP, Lodhi S. Chapter 18 - Role
doi: 10.1016/j.biotechadv.2018.11.005
of flavonoids in management of inflammatory disorders. In:
6. Maleki SJ, Crespo JF, Cabanillas B. Anti-inflammatory Watson RR, Preedy VR, editors. Bioactive Food as Dietary
effects of flavonoids. Food Chem. 2019;299:125124. Interventions for Arthritis and Related Inflammatory Diseases.
2 ed. United States: Academic Press; 2019. p. 293-322.
nd
doi: 10.1016/j.foodchem.2019.125124
18. Ginwala R, Bhavsar R, Chigbu DI, Jain P, Khan ZK. Potential
7. Hosseinzade A, Sadeghi O, Biregani AN, Soukhtehzari S,
Brandt GS, Esmaillzadeh A. Immunomodulatory effects of role of flavonoids in treating chronic inflammatory diseases
flavonoids: Possible induction of T CD4+ regulatory cells with a special focus on the anti-inflammatory activity of
through suppression of mTOR pathway signaling activity. apigenin. Antioxidants (Basel). 2019;8(2):35.
Front Immunol. 2019;10:51. doi: 10.3390/antiox8020035
doi: 10.3389/fimmu.2019.00051 19. Lilamand M, Kelaiditi E, Guyonnet S, et al. Flavonoids
and arterial stiffness: Promising perspectives. Nutr Metab
8. Hashemzaei M, Delarami Far A, Yari A, et al. Anticancer
and apoptosis-inducing effects of quercetin in vitro and in Cardiovasc Dis. 2014;24(7):698-704.
vivo. Oncol Rep. 2017;38(2):819-828. doi: 10.1016/j.numecd.2014.01.015
doi: 10.3892/or.2017.5766 20. Shen N, Wang T, Gan Q, Liu S, Wang L, Jin B. Plant
9. Demirel S. Rosa damascena miller essential oil relaxes rat flavonoids: Classification, distribution, biosynthesis, and
trachea via KV channels, KATP channels, and BKCa channels. antioxidant activity. Food Chem. 2022;383:132531.
Prostaglandins Other Lipid Mediat. 2022;163:106673. doi: 10.1016/j.foodchem.2022.132531
doi: 10.1016/j.prostaglandins.2022.106673 21. Jaakola L, Hohtola A. Effect of latitude on flavonoid biosynthesis
in plants. Plant Cell Environ. 2010;33(8):1239-1247.
10. Demirel S. Rosa damascena miller essential oil relaxes rat
thoracic aorta through the NO-cGMP-dependent pathway. doi: 10.1111/j.1365-3040.2010.02154.x
Prostaglandins Other Lipid Mediat. 2022;162:106661.
22. Ku YS, Ng MS, Cheng SS, et al. Understanding the composition,
doi: 10.1016/j.prostaglandins.2022.106661 biosynthesis, accumulation and transport of flavonoids in crops
11. Demirel S. Geraniol and β-citronellol participate in the for the promotion of crops as healthy sources of flavonoids for
vasorelaxant effects of Rosa damascena miller essential oil human consumption. Nutrients. 2020;12(6):1717.
on the rat thoracic aorta. Fitoterapia. 2022;161:105243. doi: 10.3390/nu12061717
doi: 10.1016/j.fitote.2022.105243 23. Spagnuolo C, Moccia S, Russo GL. Anti-inflammatory
effects of flavonoids in neurodegenerative disorders. Eur J
12. Demirel S. Medical evaluation of the antimicrobial activity
of rose oil on some standard bacteria strains and clinical Med Chem. 2018;153:105-115.
isolates. Altern Ther Health Med. 2022;28(6):52-56. doi: 10.1016/j.ejmech.2017.09.001
13. Bjørklund G, Dadar M, Chirumbolo S, Lysiuk R. Flavonoids 24. Barreca D, Mandalari G, Calderaro A, et al. Citrus flavones:
as detoxifying and pro-survival agents: What’s new? Food An update on sources, biological functions, and health
Chem Toxicol. 2017;110:240-250. promoting properties. Plants (Basel). 2020;9(3):288.
doi: 10.1016/j.fct.2017.10.039 doi: 10.3390/plants9030288
Volume 3 Issue 2 (2024) 15 doi: 10.36922/gtm.2458

