Page 36 - GTM-3-2
P. 36
Global Translational Medicine Impact of flavonoids on vascular health
25. Lu Y, Zhang C, Bucheli P, Wei D. Citrus flavonoids in fruit 35. Braicu C, Pilecki V, Balacescu O, Irimie A, Neagoe IB. The
and traditional Chinese medicinal food ingredients in relationships between biological activities and structure of
China. Plant Foods Hum Nutr. 2006;61(2):57-65. flavan-3-ols. Int J Mol Sci. 2011;12(12):9342-9353.
doi: 10.1007/s11130-006-0014-8 doi: 10.3390/ijms12129342
26. Su J, Xu HT, Yu JJ, et al. Luteolin ameliorates hypertensive 36. Al-Dashti YA, Holt RR, Stebbins CL, Keen CL, Hackman RM.
vascular remodeling through inhibiting the proliferation Dietary flavanols: A review of select effects on vascular
and migration of vascular smooth muscle cells. Evid Based function, blood pressure, and exercise performance. J Am
Complement Alternat Med. 2015;2015:364876. Coll Nutr. 2018;37(7):553-567.
doi: 10.1155/2015/364876 doi: 10.1080/07315724.2018.1451788
27. Gao HL, Yu XJ, Feng YQ, et al. Luteolin attenuates 37. Haskell-Ramsay CF, Schmitt J, Actis-Goretta L. The impact
hypertension via inhibiting NF-κB-mediated inflammation of epicatechin on human cognition: The role of cerebral
and PI3K/Akt signaling pathway in the hypothalamic blood flow. Nutrients. 2018;10(8):986.
paraventricular nucleus. Nutrients. 2023;15(3):502.
doi: 10.3390/nu10080986
doi: 10.3390/nu15030502
38. Barreca D, Gattuso G, Bellocco E, et al. Flavanones: Citrus
28. Chagas M, Behrens MD, Moragas-Tellis CJ, Penedo GX, Silva phytochemical with health-promoting properties. Biofactors.
AR, Gonçalves-de-Albuquerque CF. Flavonols and flavones 2017;43(4):495-506.
as potential anti-inflammatory, antioxidant, and antibacterial
compounds. Oxid Med Cell Longev. 2022;2022:9966750. doi: 10.1002/biof.1363
doi: 10.1155/2022/9966750 39. Liu Y, Niu L, Cui L, et al. Hesperetin inhibits rat coronary
constriction by inhibiting Ca(2+) influx and enhancing
29. Sharma D, Shree B, Kumar S, Kumar V, Sharma S, Sharma S. voltage-gated K(+) channel currents of the myocytes. Eur J
Stress induced production of plant secondary metabolites in Pharmacol. 2014;735:193-201.
vegetables: Functional approach for designing next generation
super foods. Plant Physiol Biochem. 2022;192:252-272. doi: 10.1016/j.ejphar.2014.03.057
doi: 10.1016/j.plaphy.2022.09.034 40. Razavi BM, Hosseinzadeh H. Chapter 34 - A review of the effects
of Citrus paradisi (grapefruit) and its flavonoids, naringin, and
30. Popiolek-Kalisz J, Fornal E. The effects of quercetin naringenin in metabolic syndrome. In: Watson RR, Preedy VR,
supplementation on blood pressure - meta-analysis. Curr editors. Bioactive Food as Dietary Interventions for Diabetes.
Probl Cardiol. 2022;47(11):101350. 2 ed. United States: Academic Press; 2019. p. 515-543.
nd
doi: 10.1016/j.cpcardiol.2022.101350 41. Salehi B, Fokou PV, Sharifi-Rad M, et al. The therapeutic
31. Barrios-Nolasco A, Domínguez-López A, Miliar-García A, potential of Naringenin: A review of clinical trials.
Cornejo-Garrido J, Jaramillo-Flores ME. Anti-inflammatory Pharmaceuticals (Basel). 2019;12(1):11.
effect of ethanolic extract from Tabebuia rosea (Bertol.) DC., doi: 10.3390/ph12010011
quercetin, and anti-obesity drugs in adipose tissue in wistar
rats with diet-induced obesity. Molecules. 2023;28(9):3801. 42. Albert NW, Lafferty DJ, Moss SM, Davies KM.
Flavonoids - flowers, fruit, forage and the future. J R Soc N Z.
doi: 10.3390/molecules28093801 2023;53(3):304-331.
32. Rahmani AH, Alsahli MA, Khan AA, Almatroodi SA. doi: 10.1080/03036758.2022.2034654
Quercetin, a plant flavonol attenuates diabetic complications,
renal tissue damage, renal oxidative stress and inflammation 43. Qi Q, Chu M, Yu X, et al. Anthocyanins and proanthocyanidins:
in streptozotocin-induced diabetic rats. Metabolites. Chemical structures, food sources, bioactivities, and product
2023;13(1):130. development. Food Rev Int. 2023;39(7):4581-4609.
doi: 10.3390/metabo13010130 doi: 10.1080/87559129.2022.2029479
33. Lin X, Han T, Fan Y, Wu S, Wang F, Wang C. Quercetin 44. Liga S, Paul C, Péter F. Flavonoids: Overview of biosynthesis,
improves vascular endothelial function through promotion biological activity, and current extraction techniques. Plants
of autophagy in hypertensive rats. Life Sci. 2020;258:118106. (Basel). 2023;12(14):2732.
doi: 10.1016/j.lfs.2020.118106 doi: 10.3390/plants12142732
34. Di Pede G, Mena P, Bresciani L, et al. Revisiting the 45. Soukup ST, Engelbert AK, Watzl B, Bub A, Kulling SE.
bioavailability of flavan-3-ols in humans: A systematic Microbial metabolism of the soy isoflavones daidzein and
review and comprehensive data analysis. Mol Aspects Med. genistein in postmenopausal women: Human intervention
2023;89:101146. study reveals new metabotypes. Nutrients. 2023;15(10):2352.
doi: 10.1016/j.mam.2022.101146 doi: 10.3390/nu15102352
Volume 3 Issue 2 (2024) 16 doi: 10.36922/gtm.2458

