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Global Translational Medicine Gelatin-based cell carriers for tooth-germ organoids

A

B

C

D

E

Figure 1. Schematic illustration of the fabrication processes for various cell carriers and the application of dental organoids. Key steps in the fabrication of
methacrylate gelatin (GelMA) microspheres (MS) (A), GelMA microparticles (MP) (B), GelMA hydrogels (HG) (C), and Gel MS (D) are shown. The use
of organoids in tooth regeneration is highlighted (E). Progenitor cells, including dental pulp stem cells (bottom) and dental epithelial cells (top), are shown.
Implantation may be performed in the mandible.
Abbreviations: APS: Ammonium persulfate; diH O: Deionized water; LAP: Lithium phenyl-2,4,6-trimethylbenzoylphosphinate; N : Nitrogen gas;
2
2
PDMS: Polydimethylsiloxane; rpm: Revolutions per minute.
Volume 4 Issue 1 (2025) 69 doi: 10.36922/gtm.5897