Page 83 - IJAMD-1-1

International Journal of AI
for Material and Design MMDB: A comprehensive biofabrication database

Figure 1. Workflow of manufacturing multi-organs database.

extracted from published research articles. Subsequently, relate to the names of individual organs, such as heart,
the collected data undergoes processing to ensure liver, and lung. Conversely, fabrication method keywords
optimal compatibility with the database. Using different primarily denote in vitro organ culture techniques, such
data processing techniques, we establish the three key as bioprinting, 3D culture, and coculture, among others.
components of the database: organs, models, and materials. To construct the search expression, we combined organ
The graphical representation in Figure 1 provides a keywords and fabrication method keywords using the
thorough understanding of the MMDB construction conjunction “AND.” The organ keywords varied according
process, elucidating the methodologies employed in its to each organ’s unique nomenclature, while the fabrication
creation. method keywords remained constant across all organs. An
illustration of this indexing approach for papers related to
2.1. Data collection in vitro heart construction is shown in Table 1. Please note
All analytical outcomes within MMDB are based on prior that “Majr” denotes a Medical Subject Headings (MeSH)
research. These results either utilize explicit information term, signifying it as a primary topic of discussion in the
obtained from online databases or involve data extraction article. MeSH is a controlled vocabulary thesaurus utilized
from scholarly articles. The primary source for these by the National Library of Medicine for indexing articles
published articles is PubMed, an established online in PubMed. In addition, we applied specific filters for the
database for health sciences literature. In addition, the papers we indexed, including a publication date range from
24
raw paper data from PubMed were enriched with metadata, 2012 to 2023, the specification that the species studied were
including information about authors, institutions, and humans, and the requirement that the publication type is
citations, through integration with the Scopus database. 25 a research paper.
We employed a specific search expression to index Within the scope of the nine systems constituting the
pertinent biofabrication papers. This search expression is human body, we gathered biofabrication research papers
bifurcated into two segments: organ-specific keywords and that focus on an array of human organs. The individual
fabrication method keywords. Organ-specific keywords count of papers dedicated to each specific organ, along with

Volume 1 Issue 1 (2024) 77 https://doi.org/10.36922/ijamd.2420