Page 265 - IJB-10-1

International

Journal of Bioprinting

RESEARCH ARTICLE
In-plane measurements and computational

fluid dynamics prediction of permeability for
biocompatible NiTi gyroid scaffolds fabricated

via laser powder bed fusion

Stanislav V. Chernyshikhin *, Biltu Mahato , Aleksei V. Shiverskii ,
1
1
1
Ivan A. Pelevin , Oleg N. Dubinin , Vladimir Yu. Egorov , Sergey G. Abaimov ,
2
1
1,3
2
and Igor V. Shishkovsky 1
1 Skolkovo Institute of Science and Technology, 121205 Moscow, Russia
2 Catalysis Lab, National University of Science and Technology MISIS, 119049 Moscow, Russia
3 World-Class Research Center, Saint Petersburg State Marine Technical University, 190121 Saint
Petersburg, Russia
Abstract

Laser powder bed fusion (LPBF) is considered a promising technology for
manufacturing porous, biomimetic, and patient-specific scaffolds for bone repair.
Scaffold permeability is one of the key factors to be considered for acquiring the
required mass-transport properties in bone tissue engineering. This study aims to
*Corresponding authors: reveal the relationship between the design parameters of gyroid-based porous
Stanislav V. Chernyshikhin
(stanislav.chernyshikhin@skoltech.ru) structure and scaffold permeability. A set of gyroid samples was manufactured from
Igor V. Shishkovsky intermetallic NiTi alloy. Nine configurations of porous structures were obtained
(i.shishkovsky@skoltech.ru) by varying the main design parameters, namely wall thickness and unit cell size.
Citation: Chernyshikhin SV, The in-plane method was employed to measure the permeability coefficient for
Mahato B, Shiverskii AV, et al. the gyroid structures. Computational fluid dynamics simulations of the porous
In-plane measurements and structures were performed to predict the targeted properties in an implant at
computational fluid dynamics
prediction of permeability for the design stage before LPBF manufacturing. The results of the simulations were
biocompatible NiTi gyroid scaffolds validated with the obtained experimental results. Geometrical accuracy and surface
fabricated via laser powder bed morphology of the as-built samples were investigated with various techniques.
fusion. Int J Bioprint. 2024;10(1):0119
doi: 10.36922/ijb.0119 Biocompatibility assessment of the gyroid scaffolds was performed with human
cell culture experiments.
Received: April 07, 2023
Accepted: May 30, 2023
Published Online: August 18, 2023 Keywords: Biomimetic implant; Laser powder bed fusion; Nickel–titanium;
Copyright: © 2023 Author(s). Gyroid structures; Permeability; Mass-transport properties
This is an Open Access article
distributed under the terms of the
Creative Commons Attribution
License, permitting distribution,
and reproduction in any medium, 1. Introduction
provided the original work is
properly cited. Implant design presents a complex problem as it lies at the intersection of engineering,
Publisher’s Note: AccScience materials science, and medicine. The development of new implant materials, configurations,
Publishing remains neutral with and applications is strongly connected with the progress in novel manufacturing
regard to jurisdictional claims in methods, primarily additive manufacturing. Strict requirements for quality and
published maps and institutional
1
affiliations. accuracy result in the widespread usage of the laser powder bed fusion (LPBF) method,

Volume 10 Issue 1 (2024) 257 https://doi.org/10.36922/ijb.0119