Page 213 - IJB-10-3
P. 213

International Journal of Bioprinting                                 Sr on GO enhances PLLA/PGA scaffold




            crack branching, crack deflection, crack pinning, crack   crack deflection, which could significantly increase the
            bridging, and pulling out also occurred, eventually   energy dissipation; however, more energy is required to
            preventing the crack from expanding further. 64-67  The   further propagate the crack after branching. At the same
            specific enhancement  mechanism  was shown  in  Figure   time, GPSr could prevent further crack propagation by
            4j. Crack bridging and pulling out occurred when the   pinning at the crack propagation tip. Ultimately, the above
            crack passed through GPSr, which could slow down the   mechanism effectively slowed down the fracture of the LG
            rupture of the LG scaffold. When the crack propagated   scaffold and improved mechanical properties.
            in the LG/GPSr1.5 scaffold, the crack was deflected and   SBF immersion experiment was conducted to
            branched due to the blocking of GPSr in the LG scaffold.   investigate  the  in vitro  biological  activity  of  the  LG/GP
            The zigzag path for crack propagation was created by   and LG/GPSr1.5 scaffolds, which was compared with that




























































            Figure 5. Surface morphology of the LG (a), LG/GP (b), and LG/GPSr1.5 scaffolds (c) immersed in SBF for 21 days, and their corresponding high-
            magnification images (d, e); EDS element mapping of the LG (g), LG/GP (h), and LG/GPSr1.5 (i) scaffolds.


            Volume 10 Issue 3 (2024)                       205                                doi: 10.36922/ijb.1829
   208   209   210   211   212   213   214   215   216   217   218