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International Journal of Bioprinting hNVU chip for brain modeling and drug screening

Figure 5. Representative expression of angiogenesis-related genes in brain tumors. (A) Expression analysis of genes related to angiogenesis and glioma
development. (B) Heatmap of gene expression profiling of typical genes in cell–cell interactions and cell–matrix interactions in the brain region at different
time points during co-culture. Data normalization was performed using the samples obtained on the first day of the model. Blue represents downregulated
gene expression, while red represents upregulated gene expression. n = 3, independent experiments. Data are presented as the mean ± S.D. Significant
differences between the groups were determined by t-test.

Volume 10 Issue 3 (2024) 351 doi: 10.36922/ijb.1684