Page 77 - IJB-10-3

International Journal of Bioprinting 3D printing technology in neurotrauma

Table 2. (Continued.....)
Applications Biomaterials Additives Printing Design In vitro/In vivo Strategies Ref.
method
Spinal cord Collagen/Chitosan BDNF Extrusion Scaffold In vitro + In vivo Com. bm + 149
injuries Neurotrophic factors
Peripheral nerve GelMA/PEGDA Platelet DLP Conduit In vitro + In vivo Com. bm + 151
injuries Neurotrophic factors
Traumatic brain Collagen/Silk MExos Extrusion Scaffold In vitro + In vivo Com. bm + Exosomes 155
injuries fibroin
Traumatic brain Collagen/Chitosan MExos Extrusion Scaffold In vitro + In vivo Com. bm + Exosomes 70
injuries
Traumatic brain Collagen/Chitosan INExos Extrusion Scaffold In vitro + In vivo Com. bm + Exosomes 154
injuries
Nervous system GelMA/PEGDA / SLA Scaffold In vitro Com. bm + Physical 122
injuries regulation
Nervous system GelMA/Graphene / SLA Scaffold In vitro Com. bm + Physical 116
injuries regulation
Peripheral nerve GelMA/PEGDA / DLP Conduit In vivo Com. bm + Physical 135
injuries regulation
Abbreviations: ABS, acrylonitrile butadiene styrene; ASCM, acellularized spinal cord matrix; BDNF, brain-derived neurotrophic factor; CNF; cellulose
nanofiber; 7,8-DHF, 7,8-Dihydroxyflavone; com.bm, composite biomaterial; DBCO, dibenzyl cyclooctyne; Dexa, dexamethasone; G-CD, gelatin-
acrylated-β-cyclodextrin; dECM, decellularized extracellular matrix; GDNF, glial cell line-derived neurotrophic factor; Gel, gelatin; GelMA, gelatin
methacryloyl; GO, graphene oxide; HA, hyaluronic acid; INExos, exosomes derived from neural stem cells pretreated with insulin-like growth factor-1;
LAP, lithium phenyl-2,4,6-trimethylbenzoylphosphinate; Me-HA, methacrylated hyaluronic acid; Me-Gel, methacrylated gelatin; MExos, human
umbilical cord mesenchymal stem cells-derived exosomes; N3, azide; N-Cad-Alg, N-Cadherin functionalized sodium alginate; NT-3, Neurotrophin-3;
NGF, nerve growth factor; nat.bm, natural biomaterial; OMT, oxymatrine; PCL, polycaprolactone; PDA, polydopamine; PEGDA, poly (ethylene glycol)
diacrylate; PLGA, poly lactic-co-glycolic acid; PLLA, poly-L-lactic acid; RGD, arginine-glycine-aspartic acid; SDF-1, stromal-derived factor 1; SF-MA,
silk fibroin glycidyl methacrylate; syn.bm, synthetic biomaterial; VEGF, vascular endothelial growth factor; XMU-MP-1, 4-((5,10-dimethyl-6-oxo-6,10-
dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino) benzenesulfonamide.

Table 3. Studies related to 3D printing combined with cell transplantation applications for neurotrauma treatment
Applications Biomaterials Cell type Printing Design In vitro/In vivo Strategies Ref.
method
Nervous system SAMA EMSCs Extrusion Scaffold In vitro Nat. bm + Stem cell 72
injuries
Nervous system GelMA DPSCs DLP Microsphere In vitro Nat. bm + Stem cell 172
injuries
Spinal cord injuries GelMA hAECs DLP Scaffold In vivo Nat. bm + Stem cell 173
Spinal cord injuries Matrigel iPSCs Extrusion Scaffold In vitro Nat. bm + Stem cell 38
Peripheral nerve GelMA ADSCs Inkjet Conduit In vitro + In vivo Nat. bm + Stem cell 174
injuries
Traumatic brain dECM NSCs Extrusion Scaffold In vitro + In vivo Nat. bm + Stem cell 102
injuries
Traumatic brain Polyurethane NSCs FDM Scaffold In vitro + In vivo Syn. bm + Stem cell 113
injuries
Spinal cord injuries PLGA SCs LDM Conduit In vitro + In vivo Syn. bm + Neural cell 178
Peripheral nerve PDA-gold/PCL BMSCs/SCs Extrusion Conduit In vitro + In vivo Syn. bm + Multiple cells 183
injuries
Nervous system PEDOT:PSS DRG cells SLA Scaffold In vitro Syn. bm + Neural cell + 128
injuries Physical regulation
(Continued.....)

Volume 10 Issue 3 (2024) 69 doi: 10.36922/ijb.2311