Page 464 - IJB-10-4

International Journal of Bioprinting Biomechanical mimic-based artificial oviduct system

mouse embryos, as it provides a physical environment that Ethics approval and consent to participate
mimics the natural conditions of the oviduct. Cells sense Not applicable.
and respond to mechanical forces and biophysical aspects
of the surrounding ECM or biomaterial. The mechanical Consent for publication
aspects of biomaterial–cell interactions can determine
the body’s reaction to a material and thus the long-term Not applicable.
therapeutic outcome for medical implants. Therefore, it
20
is essential to consider mechanical forces in engineering Availability of data
biomaterials to interface with the body and implantation Data are available from the corresponding author upon
of therapeutic cells or tissue constructs. reasonable request.
39
5. Conclusion References
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Figure 1, created using BioRender and Autodesk Inventor challenges. Fertil Steril. 2023;120:506-520.
2023 software. doi: 10.1016/j.fertnstert.2023.06.005

Funding 5. Matsuzaki S. Mechanobiology of the female reproductive
system. Reprod Med Biol. 2021;20:371-401.
This research was supported by a grant from the National doi: 10.1002/rmb2.12404
Research Foundation of Korea (2019R1A2C1086882), the 6. Hawkins J, Miao X, Cui W, Sun Y. Biophysical optimization
Korean Health Technology R&D Project (HI21C1713), of preimplantation embryo culture: what mechanics can
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Foundation (20023549) funded by the Ministry of the doi: 10.1093/molehr/gaaa087
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doi: 10.1111/cpr.12754
The authors declare no conflicts of interest.
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Author contributions oviduct: from sperm selection to the epigenetic landscape of
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Dahong Kim 9. Korenaga M, Kadota, T. Changes in mechanical properties
Formal analysis: Geehong Kim of the circular muscle of the isthmus of the human fallopian
Investigation: Min Jeong Cho, Yu Jin Kim tube in relation to hormonal domination and postovulatory
Methodology: JuYi Jang, Seon Ju Yeo time. Fertil Steril. 1981;36:343-350.
Writing – original draft: Yun Dong Koo, Min-Hee Kang, doi: 10.1016/s0015-0282(16)45736-5
Dahong Kim 10. Aviles M, Gutierrez-Adan A, Coy P. Oviductal secretions:
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Volume 10 Issue 4 (2024) 456 doi: 10.36922/ijb.3346