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REVIEW ARTICLE

           Revealing emerging science and technology research for

           dentistry applications of 3D bioprinting


           Marisela Rodriguez-Salvador *, Laura Ruiz-Cantu    2
                                         1
           1 Tecnologico de Monterrey, Escuela de Ingenieria y Ciencias, Monterrey, N.L., Mexico
           2 Centre for Additive Manufacturing, The University of Nottingham, Nottingham, UK

           Abstract: Science and technology (S&T) on three-dimensional (3D) bioprinting is growing at an increasingly accelerated
           pace; one major challenge represents how to develop new solutions for frequent oral diseases such as periodontal problems
           and loss of alveolar bone. 3D bioprinting is expected to revolutionize the health industry in the upcoming years. In dentistry,
           this technology can become a significant contributor. This study applies a Competitive Technology Intelligence methodology
           to uncover the main S&T drivers in this domain. Looking at a 6-year period from 2012 to 2018 an analysis of scientific and
           technology production was made. Three principal S&T drivers were identified: Scaffolds development, analysis of natural and
           synthetic materials, and the study of scaffold characteristics. Innovative hybrid and multiphasic scaffolds are being developed
           to regenerate periodontal tissue and alveolar bone by combining them with stem cells from the pulp or periodontal ligament.
           To improve scaffolds performance, biodegradable synthetic polymers are often used in combination with bioceramics. The
           characteristics of scaffolds such as fiber orientation, porosity, and geometry, were also investigated. This research contributes to
           people interested in bringing innovative solutions to the health industry, particularly by applying state-of-the-art technologies
           such as 3D bioprinting, in this case for dental tissues and dental bone diseases.
           Keywords: Competitive technology intelligence; three-dimensional bioprinting; dentistry; dental; Science and technology trends.

           *Correspondence to: Marisela Rodriguez-Salvador, Tecnologico de Monterrey, Escuela de Ingenieria y Ciencias, Mexico;
           marisrod@tec.mx
           Received: October 31, 2018; Accepted: December 4, 2018; Published Online: December 26, 2018

           Citation: Rodriguez-Salvador M, Ruiz-Cantu L, 2018. Revealing emerging science and technology research for dentistry
           applications of 3D bioprinting. Int J Bioprint, 5(1): 170. http://dx/doi.org/10.18063/ijb.v5i1.170

           1. Background                                       that could have a major impact in many fields including
                                                               complex organs study, ophthalmology, drug delivery, and
           Over the past few years, three-dimensional (3D) printing   so forth. In the realm of dentistry, one of the most frequent
           has attracted the attention of the science and technology   illness concerns is periodontal diseases and the loss of
           (S&T) community. Since Chuck Hull’s invention of    alveolar bone. In this context, the current research applies
           stereolithography, which was patented in 1984, new   a Competitive Technology Intelligence methodology to
           technologies and applications in a variety of industries   uncover principal S&T trends.
           have been emerging; and since the early 2000s, their
           applications have sky-rocketed. Although conventional   1.1 Competitive Technology Intelligence
           use of 3D printing technology is becoming increasingly   Competitive intelligence is based on the systematic and
           accessible to people, applications in the health industry   ethical process of gathering, analyzing and transforming
           are still in a nascent stage, particularly those that involve   information  into actionable  knowledge in the context
           bioprocesses to prevent, maintain, or heal body tissue.  of the competitive  environment  of an organization ;
                                                                                                            [1]
             3D bioprinting  technology  opens a large innovative   it contributes to making decisions in organizations of
           window, giving the potential to bring in new solutions   all  sizes  and  across  different  disciplines.  Specifically,
           Revealing emerging science and technology research for dentistry applications of three-dimensional bioprinting © 2019 Rodriguez-Salvador and Ruiz-Cantu. This
           is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.
           org/licenses/by-nc/4.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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