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Graphene oxide accelerates degradation of poly-l-lactic acid scaffold
hydrophilic properties of scaffold, the water Similarly, water absorption increased with the
uptake of the scaffold was evaluated. The water introduction of GO due to a large amount of
absorption of the PLLA scaffold increased with hydrophilic groups on the surface of GO, which
the immersion time, while the slope of the enhanced the water absorption capacity of
increase in water absorption rate was decreased. scaffold.

A B C

D E

F G H

I J K

Figure 3. (A-E) The mass loss ratio and degradation morphology of PLLA scaffolds with 0%, 0.3%,
0.6%, 0.9%, and 1.2 wt % GO after immersing in PBS solution for 1, 2, 3, and 4 weeks, respectively.
(F-J) Three-dimensional surface morphologies of PLLA/GO samples with 0%, 0.3%, 0.6%, 0.9%, and
1.2% GO after degradation for 4 weeks. (J) Surface roughness (Ra, Rq, and Rz) date of different ratios of
PLLA/GO samples. Degradation of PLLA accelerated and surface roughness increased with increasing
GO content.

96 International Journal of Bioprinting (2020)–Volume 6, Issue 1