Page 75 - IJB-6-1

Lee, et al.
compatibility are needed when adopting such file 8. Ozbolat IT, Hospodiuk M, 2016, Current Advances and Future
segmentation method across different bioprinter Perspectives in Extrusion-based Bioprinting. Biomaterials,
setup. Fragmenting CAD models and printing 3D 76:321–343. DOI: 10.1016/j.biomaterials.2015.10.076.
bioprinted models into small section invoke novel 9. Lee H, Ahn S, Bonassar LJ, et al., 2013, Cell-laden
bioprinting approaches for structures that are Poly(varepsilon-Caprolactone)/Alginate Hybrid Scaffolds
more organic and closer to nature. Future studies Fabricated by an Aerosol Cross-Linking Process for
may include cells in the build material printing to Obtaining Homogeneous Cell Distribution: Fabrication,
study cell responses with the improved BioSeg file Seeding Efficiency, and Cell Proliferation and Distribution.
processing method. Tissue Eng Part C Methods, 19:784–793. DOI: 10.1089/ten.
tec.2012.0651.
Acknowledgment 10. Billiet T, Gevaert E, De Schryver T, et al., 2014, The 3D

This research is supported by the National Printing of Gelatin Methacrylamide Cell-laden Tissue-
Research Foundation, Prime Minister’s Office, engineered Constructs with High Cell Viability. Biomaterials,
Singapore under its Medium-Sized Centre funding 35:49–62. DOI: 10.1016/j.biomaterials.2013.09.078.
scheme and by NTU startup grant. 11. Duan B, Hockaday LA, Kang KH, et al., 2013, 3D Bioprinting
of Heterogeneous Aortic Valve Conduits with Alginate/
Conflicts of interest Gelatin Hydrogels. J Biomed Mater Res A, 101:1255–1264.
DOI: 10.1002/jbm.a.34420.
There are no conflicts of interest to declare. 12. Fedorovich NE, Wijnberg HM, Dhert WJ, et al., 2011,
References Distinct Tissue Formation by Heterogeneous Printing of
Osteo and Endothelial Progenitor Cells. Tissue Eng Part A,
1. Zhuang P, Sun AX, An J, et al., 2018, 3D Neural Tissue 17:2113–2121. DOI: 10.1089/ten.tea.2011.0019.
Models: From Spheroids to Bioprinting. Biomaterials, 13. Huang Y, He K, Wang X, 2013, Rapid Prototyping of a
154:113–133. DOI: 10.1016/j.biomaterials.2017.10.002. Hybrid Hierarchical Polyurethane-Cell/Hydrogel Construct
2. Ng WL, Chua CK, Shen YF, 2019, Print Me An Organ! Why for Regenerative Medicine. Mater Sci Eng C Mater Biol
We Are Not There Yet. Prog Polym Sci, 97:101145. DOI: Appl, 33:3220–3229. DOI: 10.1016/j.msec.2013.03.048.
10.1016/j.progpolymsci.2019.101145. 14. Ozbolat IT, Chen H, Yu Y, 2014, Development of “Multi-Arm
3. Kolan KCR, Semon JA, Bromet B, et al., 2019, Bioprinting Bioprinter” for Hybrid Biofabrication of Tissue Engineering
with Human Stem Cells-Laden Alginate-gelatin Bioink and Constructs. Robot. Comput. Integr. Manuf, 30:295–304. DOI:
Bioactive Glass for Tissue Engineering. Int J Bioprint, 5:13. 10.1016/j.rcim.2013.10.005.
DOI: 10.18063/ijb.v5i2.2.204. 15. Shim JH, Lee JS, Kim JY, et al., 2012, Bioprinting of a
4. Xu T, Zhao W, Zhu JM, et al., 2013, Complex Heterogeneous Mechanically Enhanced Three-dimensional Dual Cell-
Tissue Constructs Containing Multiple Cell Types Prepared Laden Construct for Osteochondral Tissue Engineering
by Inkjet Printing Technology. Biomaterials, 34:130–139. Using a Multi-Head Tissue/Organ Building System.
DOI: 10.1016/j.biomaterials.2012.09.035. J Micromech Microeng, 22:085014. DOI: 10.1088/0960-
5. Guillemot F, Guillotin B, Fontaine A, et al., 2011, Laser- 1317/22/8/085014.
assisted Bioprinting to Deal with Tissue Complexity in 16. Snyder JE, Hamid Q, Wang C, et al., 2011, Bioprinting Cell-
Regenerative Medicine. MRS Bull, 36:1015–1019. DOI: laden Matrigel for Radioprotection Study of Liver by Pro-drug
10.1557/mrs.2011.272. Conversion in a Dual-tissue Microfluidic Chip. Biofabrication,
6. Lee YB, Polio S, Lee W, et al., Bio-printing of Collagen 3:034112. DOI: 10.1088/1758-5082/3/3/034112.
and VEGF-Releasing Fibrin Gel Scaffolds for Neural Stem 17. Visser J, Peters B, Burger TJ, et al., 2013, Biofabrication of Multi-
Cell Culture. Exp Neurol, 223:645–652. DOI: 10.1016/j. material Anatomically Shaped Tissue Constructs. Biofabrication,
expneurol.2010.02.014. 5:035007. DOI: 10.1088/1758-5082/5/3/035007.
7. Skardal A, Mack D, Kapetanovic E, et al., 2012, Bioprinted 18. Lee W, Lee V, Polio S, et al., 2009, Three-dimensional Cell-
Amniotic Fluid-derived Stem Cells Accelerate Healing of hydrogel Printer Using Electromechanical Microvalve for
Large Skin Wounds. Stem Cells Transl Med, 1:792–802. Tissue Engineering. In: Solid-State Sensors, Actuators and
DOI: 10.5966/sctm.2012-0088. Microsystems Conference, 2009. TRANSDUCERS 2009,
International Journal of Bioprinting (2020)–Volume 6, Issue 1 71