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ORIGINAL ARTICLE

           Development of a 3D-printed Medication Label for the

           Blind and Visually Impaired



           Yijun Wong , Yihua Xu , Lifeng Kang *, Kevin Yi-Lwern Yap *
                                   2,3
                                                  2
                                                                           4
                       1
           1 Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
           2 School of Pharmacy, Faculty of Medicine and Health, University of Sydney, Pharmacy and Bank Building A15, Science
           Road, NSW 2006, Sydney, Australia
           3 College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China
           4 Department of Public Health, School of Psychology and Public Health, La Trobe University, Melbourne, Australia


           Abstract: This study explored the potential of three-dimensional printing (3DP) technology in producing a three-dimensional
           (3D) medication label for blind and visually impaired (BVI) patients to ease their drug administration. Different variations of
           label wordings, dosing instructions, and medication identifiers were designed with reference to guidelines by the American
           Foundation for the Blind. Shapes and symbols were used as dosing instructions and medication identifiers to the patient’s
           medical conditions. Prototype designs were created with common graphics computer-assisted drafting software and 3D-
           printed using acrylonitrile butadiene styrene as the polymer filament. Feedback was then obtained from five people with
           normal vision and four BVI persons. The initial prototype comprised four components, namely, medication name and strength,
           patient’s  name,  dosing  instruction,  and  medication  identifier. A  revised  label  comprising  the  latter  two  components  was
           developed after feedback by BVI persons. Words were in all uppercase and regular font type, with a 5-mm center-to-center
           letter spacing. Elevation heights of the letters alternated between 1 mm and 1.5 mm. A half sphere represented the medication
           dose unit, while vertical lines and a horizontal center line with alternating elevation of arrowheads represented the frequency
           of administration and the medication’s consumption in relation to food, respectively. Symbols based on target organs were
           used as medication identifiers. With rapid advancements in 3DP technologies, there is tremendous potential for producing 3D
           labels in patients’ medication management.

           Keywords: Blind, Medication label, Pharmacy, Prescription label, Three-dimensional printing, Visually impaired

           *Corresponding Authors: Lifeng Kang, Email: lifeng.kang@sydney.edu.au and Kevin Yi-Lwern Yap, Email: K.Yap@latrobe.edu.au
           Received: April 10, 2020; Accepted: April 21, 2020; Published Online: April 30, 2020
           Citation: Wong Y, Xu Y, Kang L, et al., 2020, Development of a 3D-printed medication label for the blind and visually
           impaired, Int J Bioprint, 6(2):276. http://dx.doi.org/10.18063/ijb.v6i2.276

           1 Introduction                                     diseases and aging processes . This is of concern as
                                                                                         [4]
                                                              the proportion of the elderly is expected to increase
           According to the World Health Organization, there   from 617 million (8.5% of the world’s population)
           are ~2.2 billion people globally estimated to be                                            [5]
           blind and visually impaired (BVI), among which     to nearly 1.6 billion (17%) by the year 2050 .
           majority are 50 years and above . In the United       While medication compliance is challenging
                                           [1]
           States, ~23.7 million American adults (61% women,   for many patients, this is even more so for BVI
           39% men) experience vision loss . The  average     patients, who face additional challenges.  The
                                            [2]
           age of these BVI persons is 62 years , which is in   World  Health  Organization  defines  low  vision
                                              [3]
           sync with the global trend. The risk of vision loss  as acuity <6/18 and blindness as acuity <3/60 .
                                                                                                            [6]
           increases exponentially with age due to chronic eye  When sight is limited or absent, these patients
           © 2020 Wong, et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International
           License (http://creativecommons.org/licenses/by-nc/4.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the
           original work is properly cited.
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