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Large-Scale AM for Manufacturing PPE during COVID-19
           in 2002 – 2004  and can be transmitted through      mass manufacturing techniques such as injection
                          [6]
           an  airborne  droplet  and  contact  transmission .   molding when increased  demand makes the
                                                        [7]
           It has also been established that people are able   production of tooling and moulds a cost-effective
           to  transmit  the  infection  despite  not  obviously   option.
           displaying symptoms (asymptomatic) .                  Due  to  the  prevalence  of  desktop  FFF  3D
                                               [8]
             For  these  reasons,  the  wearing  of  personal   printers, most of the designs being manufactured
           protective  equipment  (PPE) has become a vital     by  these  global  communities  are  optimized  for
           requirement for frontline medical staff, those with   common 3D printer formats, such as build plates
           critical  caring  responsibilities  and key workers   of  approximately  200  ×  200  mm  and  0.4  mm
           facing  increased  potential  exposure  to  SARS-   (sub-mm) extrusion nozzles . These limitations
                                                                                          [16]
           Cov-2.  The  WHO  has  recommended  that  PPE       generally  mean  that  the main  components  of
           also includes eye protection to safeguard against   face shields can take 1 – 2 h to produce, which
           droplet  and airborne  transmission .  Droplet      presents  a  significant  issue  for  producing  larger
                                               [9]
           transmission  (as  happens  with  influenza)  occurs   volumes  of  components.  Typical  thermoplastic
           when droplets from an infected individual  that     deposition  rates  on  desktop  3D printers  are
           is generated during coughing, sneezing, or even     usually on the order of 10 mm /s . Large-scale
                                                                                             3
                                                                                                [17]
           talking pass through the air and land on the eyes,   additive  manufacturing  (LSAM) systems have
           nose, and mouth of another individual leading to    built volumes with dimensions of 1 m or greater
           infection .                                         and  typically  use  nozzles  with  diameters  of
                   [10]
             With  this  increased  global  demand  for  PPE,   1 mm or greater, allowing for significantly higher
           governments  and  organizations  have  struggled    deposition rates on the order of 100 mm /s. LSAM
                                                                                                    3
           to source enough for millions of regular PPE        has been used previously to manufacture tooling
           users,  let alone for non-typical users  such as    for various applications [18-20] , as well as being used
           pharmacies and general practitioners  who  are      for direct manufacture  of large single objects
                                                                                                            [21]
           now at increased risk of infection  during their    such as furniture  and bike frames .
                                                                               [22]
                                                                                                 [23]
           daily  activities.  These  supply  chain  issues  have   The ability to deposit thermoplastic materials
           arisen due to a global shortage of PPE items such   at rates of up to 100 mm /s with LSAM means that
                                                                                     3
           as eye protection/face shields and the inability to   bridge manufacturing rates for PPE components
           manufacture  enough items quick enough .  In        can  be  significantly  increased  addressing
                                                    [11]
           response to this  unprecedented  demand,  many      immediate requirements in advance of an eventual
           companies, academic institutions, and individuals   increase in production capacity using techniques
           have  sought  to  use  democratized  manufacturing   such  as  injection  molding.  In  this  paper,  we
           facilities and equipment such as three-dimensional   report the design and development of face shield
           (3D) printers (generally fused filament fabrication   components  optimized  for  production  using
           [FFF] systems) to produce components for much       LSAM  technology such that a component that
           needed  PPE items  such as face  shields   [12,13] .   would normally take 1 – 2 h to produce can be
           This  manufacturing  effort  has  seen  members  of   made in under 5 min. The development of process
           the  international  3D printing  community  come    parameters to ensure continued part quality with
           together  in  vast,  rapidly  formed  collaborative   larger  part  volumes  per  production  run is also
           networks to address the PPE shortfall  in a way     presented.
           reminiscent  of the often-proposed concept of
           localized microfactories [14,15] . In the context of a   2 Materials and methods
           traditional product development cycle, this type of
           activity can be likened to bridge manufacturing,    The headbands were printed on a 3D Platform 300
           where the use of additive manufacturing techniques   Series Workbench Pro (3D Platform, USA) with
           is used to bridge the gap between small volume,     High  Flow  Extruder  300  3D  Printer  Extruder,
           time-intensive manufacturing processes, and other   fitted  with  a  1.8  mm  nozzle.  The  material  used

           52                          International Journal of Bioprinting (2020)–Volume 6, Issue 4
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