Page 53 - IJB-10-6
P. 53

International Journal of Bioprinting                               Semi-solid extrusion for pediatric medicine




             Table 1. Commented bibliographical review (2021–2024) on the use of 3D printing for semi-solid extrusion (SSE) according to the different pharmaceutical forms
                                                                                                          Continued
                   Ref.   82   83     84            85     86   87         88    89   90         91




                           Development of caffeine-containing printlets for  neonates suffering from apnea of prematurity In vivo assessment (in rats) of L-arginine-loaded  cranberry leaf extract bioactivity on insulin resistance  and development of 3D-printed dosage forms  Bioequivalence assessment of solid oral dosage forms of  sildenafil manufactured by SSE within hospital pharmacy  vs. industrial sildenafil tablets; sildenafil was selected  for its treatment of pulmon











                   Commentaries                          macromolecules        dosage form  and MESO-PP  mass)  and drug release









                           Sodium alginate; HPMC; sodium   Gelucire ®  48/16; glycerol  Carbopol 974P NF, HPMC 2910, corn   Carboxymethyl cellulose sodium, glycerin,  water, poly(ε-caprolactone), medium chain   triglycerides, polysorbate 80  Sodium alginate, mannitol  Polyethylene glycol 1500, propylene glycol,  poloxamer 188, ultrapure water  HPMC K15M CR, EC 20, PVP k30,  poloxamer 188, carbomer 934P,



               produced and their composition (active pharmaceutical ingredient [API] and excipients)



                   Excipients  croscarmellose  Polyethylene oxide  starch  HPMC        HPMC, PVP, SiO 2  nano-CaCO 3










                   API     Caffeine  Cranberry leaf   extracts  Sildenafil citrate    (10 mg)  Octréotide acetate   (3.4%)  Paracetamol  Resveratrol,   curcumin  Flurbiprofen (15%)  Albendazole  Tranexamic acid or   paracetamol  Clarithromycin



                   Formulation details    and properties  Immediate release printlets  Immediate release printlets  Immediate release printlets  Gastro-resistant delayed-  release printlets  Immediate-release printlets   with porous geometry  Controlled release re-  dispersible 3D-printed   nanomedicines  Immediate-release printlets  Immediate-release printlets  Swallowable printlets with   several drug release profiles  Gastric floating delivery   system with 8 h sustain









                   Formulation type  Oral dosage forms           Swallowable printlets









            Volume 10 Issue 6 (2024)                        45                                doi: 10.36922/ijb.4063
   48   49   50   51   52   53   54   55   56   57   58