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International Journal of Bioprinting Semi-solid extrusion for pediatric medicine
Table 1. Commented bibliographical review (2021–2024) on the use of 3D printing for semi-solid extrusion (SSE) according to the different pharmaceutical forms
Continued
Ref. 82 83 84 85 86 87 88 89 90 91
Development of caffeine-containing printlets for neonates suffering from apnea of prematurity In vivo assessment (in rats) of L-arginine-loaded cranberry leaf extract bioactivity on insulin resistance and development of 3D-printed dosage forms Bioequivalence assessment of solid oral dosage forms of sildenafil manufactured by SSE within hospital pharmacy vs. industrial sildenafil tablets; sildenafil was selected for its treatment of pulmon
Commentaries macromolecules dosage form and MESO-PP mass) and drug release
Sodium alginate; HPMC; sodium Gelucire ® 48/16; glycerol Carbopol 974P NF, HPMC 2910, corn Carboxymethyl cellulose sodium, glycerin, water, poly(ε-caprolactone), medium chain triglycerides, polysorbate 80 Sodium alginate, mannitol Polyethylene glycol 1500, propylene glycol, poloxamer 188, ultrapure water HPMC K15M CR, EC 20, PVP k30, poloxamer 188, carbomer 934P,
produced and their composition (active pharmaceutical ingredient [API] and excipients)
Excipients croscarmellose Polyethylene oxide starch HPMC HPMC, PVP, SiO 2 nano-CaCO 3
API Caffeine Cranberry leaf extracts Sildenafil citrate (10 mg) Octréotide acetate (3.4%) Paracetamol Resveratrol, curcumin Flurbiprofen (15%) Albendazole Tranexamic acid or paracetamol Clarithromycin
Formulation details and properties Immediate release printlets Immediate release printlets Immediate release printlets Gastro-resistant delayed- release printlets Immediate-release printlets with porous geometry Controlled release re- dispersible 3D-printed nanomedicines Immediate-release printlets Immediate-release printlets Swallowable printlets with several drug release profiles Gastric floating delivery system with 8 h sustain
Formulation type Oral dosage forms Swallowable printlets
Volume 10 Issue 6 (2024) 45 doi: 10.36922/ijb.4063

