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International Journal of Bioprinting Semi-solid extrusion for pediatric medicine

Figure 2. SSE 3D printing extrusion mechanisms: pneumatic extrusion including (A1) valve-free and (A2) valve-based. Adapted with permission from
80
ref. Copyright © 2024 Elsevier.

Figure 3. SSE 3D printing extrusion mechanisms: mechanical extrusion including (B1) piston- or (B2) screw-driven. Adapted with permission from ref. 80
Copyright © 2024 Elsevier.

like the anti-infective drug-loaded urinary catheter made solid oral dosage forms (Table 1), including chewable
by Archana et al. The articles reviewed report different formulations. For example, Rouaz-El Hajoui et al.
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drug release kinetics (immediate or controlled release), developed a gastro-resistant form produced by SSE from
demonstrating the versatility of SSE for producing variants a hydrogel loaded with pellets containing an API sensitive
of the same drug. Except for orodispersible forms, which to the stomach’s acidic pH. This example demonstrates
are primarily advantageous for their rapid release of that the formulation of a chewable form is compatible with
APIs, controlled release kinetics are found among all the modified release kinetics.

Volume 10 Issue 6 (2024) 50 doi: 10.36922/ijb.4063