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Topology Optimized Locking Compression Plates to Minimize Stress Shielding
           and lower computational time, while finer mesh increases   integrity, while values lower than 25% have no significant
           the volume reduction  and the computational  time.  As   effect  on  the  stiffness  reduction.  The  corresponding
           observed, no significant difference in equivalent stiffness   equivalent stiffness values are presented in Tables 3-6. In
           values will be obtained if elements were to be increased   all cases, the equivalent stiffness decreases by increasing
           more than 400,000 elements and the computational cost   the  volume  reductions,  confirming  previously  reported
           will significantly increase.                        observations for  TO of 2D plates . Several  authors
                                                                                             [12]
               Figures  5-8  present  the  optimized  designs for   observed similar  results using  TO to address stress
           all plates (eight-, six-, and four- screw holes), different   shielding by redesigning orthopedic implants in the case
           loading conditions, and volume reduction.  Imposed   of pelvic  prosthetics , hip  prosthetics,  and  spine
                                                                                 [19]
                                                                                                  [20]
           volume reductions vary between 25% and 75% as values   implants . The results also indicate that the mechanical
                                                                      [21]
           higher  than  75%  can  jeopardize  the  design’s  structural   properties are directly related to the material volume as



























           Figure 5. Topology-optimized plates under compression conditions.
































           Figure 6. Topology-optimized plates under bending loading conditions.

           158                         International Journal of Bioprinting (2021)–Volume 7, Issue 3
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