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CTP Scaffolds Treated Bone Defects
CFZ-incorporated scaffolds, which are produced by 3D 6. Lee JY, Son SJ, Son JS, et al., 2016, Bone-Healing Capacity
printing, in promoting bone regeneration in critical-sized of PCL/PLGA/Duck Beak Scaffold in Critical Bone Defects
bone defects. in a Rabbit Model. Biomed Res Int, 2016:2136215.
Acknowledgments https://doi.org/10.1155/2016/2136215
7. Walsh WR, Vizesi F, Michael D, et al., 2008, Bruceβ-TCP
This work was supported by Guangxi Science and Bone Graft Substitutes in a Bilateral Rabbit Tibial Defect
Technology Program (2018GXNSFAA294116, Model. Biomaterials, 29:266–71.
2018GXNSFAA138074,2018GXNSAA294091), Guangxi
key R & D Project (Guike AB18050008), Scientific https://doi.org/10.1016/j.biomaterials.2007.09.035
Research Project of High-level talents in the affiliated 8. Huang J, Liu W, Liang Y, et al., 2018, Preparation and
Hospital of Youjiang Medical College for nationalities Biocompatibility of Diphasic Magnetic Nanocomposite
(R20196301, R20196306), High-level Innovation team Scaffold. Mater Sci Eng C Mater Biol Appl, 87:70–7.
and Outstanding Scholars Program of Colleges and 9. Ji C, Annabi N, Khademhosseini A, et al., 2011, Fabrication
Universities in Guangxi: innovative team of basic and of Porous Chitosan Scaffolds for Soft Tissue Engineering
Clinical Comprehensive Research on Bone and Joint using Dense Gas Co . Acta Biomater, 7:1653–64.
degenerative Diseases. 2
https://doi.org/10.1016/j.actbio.2010.11.043
Conflicts of interest 10. Hartgerink JD, Beniash E, Stupp SI, 2002, Peptide-Amphiphile
NanofibersA Versatile Scaffold for the Preparation of Self-
The authors have no conflict of interest to declare.
Assembling Materials. Proc Natl Acad Sci USA, 99:5133–8.
Author contributions https://doi.org/10.1073/pnas.072699999
K L., J L. and YJ T. conceived the project. Y L. KG X. and 11. Green JD, Tollemar V, Dougherty M, et al., 2015, Multifaceted
C W. conducted the scaffold fabrication, characterization. Signaling Regulators of ChondrogenesisImplications in
CL Y., GF D., GG H. and K H. conducted the in vitro Cartilage Regeneration and Tissue engineering. Genes Dis,
release/degradation test and in vitro cell culture. F L., CC 2:307–27.
Z., SJ D. and J C. conducted the in vivo experiments in rat 12. Gaasbeek RD, Toonen HG, van Heerwaarden RJ, et al., 2005,
cranial defects and analyzed the related data. QY L., J L. Mechanism of Bone Incorporation of β-TCP Bone Substitute
and LQ W. contributed to the writing of the manuscript.
in Open Wedge Tibial Osteotomy in Patients. Biomaterials,
References 26:6713–9.
https://doi.org/10.1016/j.biomaterials.2005.04.056
1. Sharif F, Ur Rehman I, Muhammad N, et al., 2016, Dental 13. Michalicka M, Boisjoli G, Jahan S, et al., 2017, Human Bone
Materials for Cleft Palate Repair. Mater Sci Eng C Mater Biol Marrow Mesenchymal Stromal Cell-Derived Osteoblasts
Appl, 61:1018–28. Promote the Expansion of Hematopoietic Progenitors
https://doi.org/10.1016/j.msec.2015.12.019 Through Beta-Catenin and Notch Signaling Pathways. Stem
2. Marx RE, 2007, Bone and Bone Graft Healing. Oral Cells Dev, 26:1735–48.
Maxillofac Surg Clin North Am, 19:455–66. https://doi.org/10.1089/scd.2017.0133
3. Agarwal R, García AJ, 2015, Biomaterial Strategies for 14. Zhang C, Hu B, Chen Y, et al., 2013, Characterization of
Engineering Implants for Enhanced Osseointegration and the Molecular Mechanism of the Bone-Anabolic Activity of
Bone Repair. Adv Drug Deliv Rev, 94:53–62. Carfilzomib in Multiple Myeloma. PLoS One, 8:e74191.
https://doi.org/10.1016/j.addr.2015.03.013 https://doi.org/10.1371/journal.pone.0074191
4. Pilliar RM, Filiaggi MJ, Wells JD, et al., 2001, Porous Calcium 15. Hurchla MA, Garcia-Gomez A, Hornick MC, et al., 2012,
Polyphosphate Scaffolds for Bone Substitute Applications- The Epoxyketone-Based Proteasome Inhibitors Carfilzomib
In Vitro Characterization. Biomaterials, 22:963–72. and Orally Bioavailable Oprozomib Have Anti-Resorptive
https://doi.org/10.1016/s0142-9612(00)00261-1 and Bone-Anabolic Activity in Addition to Anti-Myeloma
5. Lai Y, Li Y, Cao H, et al., 2019, Osteogenic Magnesium Effects. Leukemia, 27:430–40.
Incorporated into PLGA/TCP Porous Scaffold by 3D Printing https://doi.org/10.1038/leu.2012.183
for Repairing Challenging Bone Defect. Biomaterials, 16. Yang Y, Blair HC, Shapiro IM, et al., 2015, The Proteasome
197:207–19. Inhibitor Carfilzomib Suppresses Parathyroid Hormone-
https://doi.org/10.1016/j.biomaterials.2019.01.013 induced Osteoclastogenesis through a RANKL-Mediated

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