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Dual-Response Composite Hydrogels
A
B
Figure 3. Images of various hydrogels under different conditions in vials on their sides. Scale bar is 1 cm. (A) The state of the hydrogel changed
with temperature before UV irradiation. (B) The state of the hydrogel changed with UV irradiation time when the temperature was 4°C.
decreased as the concentration of HAMA increased, and ambient temperatures (Figure S4). Therefore, the optimal
for CN+1%HAMA hydrogels, the curing time was 5 min. parameters for CN+1%HAMA hydrogels in the next 3D
As a control, CN-related hydrogels were reversibly printing step were 30°C and 15 mW/cm UV irradiation
2
temperature-sensitive, whereas MA-related hydrogels for 5 min. The responsiveness of CN+1%HAMA to
solidified after UV irradiation. After 5 min of UV temperature and UV irradiation allows it to be used as a
irradiation, the cured hydrogel remained solid at various type of controllable printed biomaterial inks.
132 International Journal of Bioprinting (2022)–Volume 8, Issue 3
