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     3D Bioprinting of Osteotomy-Aided Module
           Figure 7. Sawbones osteotomy models.
                        A                                      B
           Figure 8. The deviation from average of mass (A) and volume (B) of every intermediate fragment was visualized with one-dimensional
           histogram.
           Here, we designed a new method of osteotomy-aided   Moreover, the process of osteotomy relies too much
           module production for bone biomechanical study with 3D   on the experience  of mechanical  researchers,  and the
           printing and CAD and verified the accuracy of osteotomy.   accuracy evaluation of osteotomy can be easily neglected.
           To the best of our knowledge, unlike the traditional design   At present, only few osteotomy-aided modules have been
           research, this is the first work that describes the design   introduced in bone biomechanical studies [8,9,12] . Windell
           of osteotomy-aided modules using 3D printing and CAD   et al. conducted a study on biomechanical comparison of
           techniques. In addition, this study provides insight into   periprosthetic femoral fracture risk in different implants
           the application of digital orthopedic technology in bone   of the composite Sawbones model. After approximately
           biomechanics.                                       determining  the  cutting  position,  a  cutting  guide  was
               The  previous  works  are some  in vitro  bone   used to ensure the standard cutting of the femur head and
           biomechanical studies focusing on the evaluation of   neck . However, the comparative analysis of osteotomy
                                                                  [8]
           mechanical advantage, dynamic stability, and post-operative   accuracy was not performed.
           implant-related complications (Table 2) [4,5,8,10,11,23,24] . The   The osteotomy-aided modules for fracture models
           pre-experiment osteotomy methods performed in these   were first proposed by Windolf et al.  They designed
                                                                                               [9]
           studies were in accordance with international fracture   a custom-made saw-guide that was fastened to the
           classifications.  However,  we  noticed  that  most  of  the   side-plate and enabled simulation of an unstable 31-B2
           studies did not involve standard osteotomy techniques.   fracture. This device could be adjusted in anteroposterior
           112                         International Journal of Bioprinting (2022)–Volume 8, Issue 4





