Page 346 - IJB-9-2

International Journal of Bioprinting Characterization of BITC antibacterial hydrogel

Figure 5. The scanning electron microscope images of XLKC-Gel and benzyl isothiocyanate-XLKC-Gel.

A

B C

Figure 6. Antibacterial activity of the benzyl isothiocyanate (BITC) hydrogel against Staphylococcus aureus and Escherichia coli. (A) Bacteriostatic zone test
of hydrogel. (B) Inhibitory effect of BITC hydrogel on E. coli biofilms. (C) Inhibitory effect of BITC hydrogel on S. aureus biofilms.
have such a morphology. These spheres can be regarded as compared with XLKC-Gel. This indicates that the addition
BITC embedded in the gel after XG emulsion. In addition, of BITC could increase the pore size of hydrogel, providing
we observed a clear reticular structure at 10× (10 µm) and a suitable environment for its subsequent use as a delivery
5× (5 µm) in the hydrogels, XLKC-Gel and BITC-XLKC- carrier of polymer drugs.
Gel, and the reticular structure was evenly distributed.
The pore size of the network structure was favorable for 3.6. Antibacterial activity of the BITC hydrogel
the release of BITC and also for sustained release. BITC- We used S. aureus to evaluate the antibacterial activity of the
XLKC-Gel had a larger pore size at the same field of view, BITC hydrogel. S. aureus is a kind of Gram-positive bacteria

Volume 9 Issue 2 (2023) 338 https://doi.org/10.18063/ijb.v9i2.671