Page 378 - IJB-9-3

International Journal of Bioprinting 3D-printed anistropic meniscus

Table 2. (Continued)
Strategies combined Materials Methods and process In vitro/ Biological effect References
with 3D printing In vivo of heterogeneity
reconstruction
PCL@ tetra-PEG 3D-printed polylactone/4 arm In vitro The anti-inflammatory [92]
poly (ethylene glycol) hydrogel and anti-oxidation effect
(PCL@ tetra-PEG) composite in regulating the complex
scaffold with Ac2-26 peptide microenvironment and
coated. promote tissue regeneration
were achieved.
SF/PCL/L7 The MSC affinity peptide, In vitro and The scaffold promoted MSC [96]
LTHPRWP (L7), was combined in vivo proliferation, differentiation
with 3D-printed SF/PCL scaffold. in vitro and biomimetic
meniscus regeneration.
SF/PVA/AESM A multi-component composite In vitro and AESM powder enhanced the [97]
SF/PVA scaffold was 3D-printed in vivo biomechanical properties of
and combined with AESM. the scaffold.
PCL-DMECM PCL scaffold and DMECM were In vitro and This dual-phase decellularized [108]
combined with the assistance of in vivo scaffold demonstrated
3D printing technique. great biocompatibility and
biomechanical property,
which further accelerate
meniscus regeneration and
delay osteoarthritis.
PU/PCL/ Cell-loaded DMECM bioink and In vitro and The scaffold facilitated [109]
DMECM polyurethane (PU)-PCL were in vivo MSCs proliferation
mixed for a 3D-printed TEM and fibrochondrogenic
differentiation.
3D bioprinting TCNF/ALG The bioink consists of hMFC In vitro The expression of COL2A1 [114]
from the partial meniscectomy in TCNF/ALG construct was
and TCNF/ALG. significantly increased.
GG/FB/Sil-MA The bioink consists of GG/FB and In vitro and The regeneration of [115]
Sil-MA was 3D-bioprinted into a in vivo fibrocartilage tissue was
hybrid structure for fibrocartilage promoted.
regeneration.
GelMA/MECM The menicus derived bioink was In vitro and The scaffold showed [116]
combined with GelMA/MECM. in vivo sufficient feasibility and
functionality in promoting
cell viability, mechanical
property, biodegradation and
tissue formation.
PCL/PLGA 3D-bioprinted anisotropic In vitro and 3D-bioprinted meniscus [104]
meniscus constructs with in vivo restored the anisotropy of
peripheral blood vessels growth native healthy meniscus with
and regional differential cell and peripheral blood vessels
ECM depositions were generated. infiltration.
Surface functional PLA/IPN The surface of 3D-printed PLA In vitro and The scaffold showed good [117]
strategies scaffold was functionalized and in vivo biocompatibility and
embedded with self-healing IPN promoted meniscus tissue
hydrogel for interface bonding. regeneration in vivo.
PU/COL-1/FN The surface of PU scaffolds was In vitro and FN coating was superior to [118]
modified by physical absorption in vivo COL-1 coating in promoting
of COL-1 and FN. various stem cell functions,
and FN was conducive to
the formation of cartilage on
scaffolds
(Contd...)

Volume 9 Issue 3 (2023) 370 https://doi.org/10.18063/ijb.693