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International Journal of Bioprinting 3D printing in bone regeneration and bone repair

Figure 5. CiteSpace network visualization of author collaboration analysis and co-cited authors of publications on three-dimensional printing in bone
regeneration and bone repair. (A) Author collaboration analysis. (B) Network visualization diagram of the co-cited authors of the publications. (C) Author
timeline visualization from 2012 to 2022. The nodes indicate author collaboration or co-cited authors. The line connecting the nodes indicates the co-
citation relationship. The node area enlarges as the number of co-citations increases. The colors represent different years; in A, the color changes from white
to green from 2012 to 2022; in B, the color changes from brown to yellow from 2012 to 2022.

all the other clusters excluding cluster 6 were current “bone morphogenetic protein” (2013–2017) and “growth
research hotspots. factor delivery” (2015–2019). Interestingly, the keywords
The CiteSpace algorithm was utilized to investigate “drug delivery system” and “progenitor cell” had the most
keyword bursts, showing the top 25 keywords with the recent burst citations during 2020–2022, suggesting that
strongest citation bursts (Figure 9). The keyword with these topics are likely to be the next potential research
the strongest citation bursts was “rapid prototyping” hotpots in the near future.
(strength = 7.05), followed by “marrow stromal cell” 4. Discussion
(strength = 5.59) and “therapy” (strength = 4.96). The
keyword with the longest burst duration was “rapid In the last decade, 3DP technology has gained significant
prototyping,” which lasted 7 years (2012–2018), followed by global research interest and proven to be a powerful tool

Volume 9 Issue 4 (2023) 323 https://doi.org/10.18063/ijb.737