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International Journal of Bioprinting                             3D-printed oblique lumbar interbody cage





































                    Figure 9. von Mises stress distributions for the intact, CA, CES, and CLS models under flexion, extension, bending, and torsion.


            this cage profile to improve overall system stability after   67%/73%/99%/97% and 75%/68%/94%/95%, respectively,
            surgery .                                          with a relative overall decrease of approximately 84% and
                  [24]
                                                               83% in ROM, respectively. The CES model demonstrated
               Metal 3D printing techniques are well-established
            for  building  complicated  3D  medical  implants  and  have   better stability among all implantations regardless of load
                                                               condition. However, the decrease in ROM of the three
            great potential to solve the problems of creating a porous   fixation methods in terms of bending and rotation was
            titanium body [11,12,24] . Many studies have indicated that   greater than that of flexion and extension, consistent with
            titanium  implants  manufactured  via  3D  printing  with  a   a previous study . Furthermore, the CES model was also
                                                                            [15]
            porous design can enhance bone stability through enough   comparable to the lateral enhanced fixation of CLS, which
            bone ingrowth [11,12,24] . Therefore, the hollow part within the   can provide higher stability especially in flexion.
            cage and exterior walls of the cage without the supporting
            solid structure was designed as grooves according to the   Excessive stress on the endplate may result in
            suggestion of the WTO analysis. This was filled with YM   destruction or fracture of the endplate. Thus, it is necessary
            lattice, which has good performance in terms of bone   to confirm whether the vertebral cage system induces
            ingrowth capability and bonded strength between the   unfavorable  stress  on  the  endplate  during  implantation.
            implant and bone. This reduces the stress-shielding effect   On FE analysis, we found that contact areas at the anterior/
            while increasing bone growth and improving overall   posterior edges between the cage and endplate during
            stability.                                         CES implantation can effectively reduce stress values and
               Lumbar interbody fusion surgery aims to increase the   distribution to decrease endplate damage and the risk of
            stability (i.e., decrease the ROM) between two vertebral   cage subsidence especially during extension. This suggests
            bodies is the main goal. The results of FE analysis showed   that our OLIF cage with the embedded fixation screws can
            that CA implantation reduced the ROM by 62%, 52%,   more effectively transmit cage force to the endplate than
            93%, and 96% under flexion, extension, lateral bending,   that with lateral plate fixation. This result was in line with
            and rotation, respectively, compared to the intact model.   the previous ROM results.
            ROM decreased by an average of about 75%. The relative   Complex contours and the internal lattice design
            decreased percentages of the CES and CLS implantations   of the OLIF cage only can be fabricated by 3D printing
            under the aforementioned four load conditions were   rather than traditional mechanical cutting. Previous


            Volume 9 Issue 5 (2023)                        455                         https://doi.org/10.18063/ijb.772
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