Page 387 - IJB-9-6

International Journal of Bioprinting Biomimetic biofabrication of tumors volume

Ref [71] [70] [72] [68] [120] [69] [121] [75] [122] [123] [76] [124] [77] [74] [81] [80] [90] [94] [97]

Macrophages migration Blood vessel-like structures Migration of fibroblasts Chimeric organoids underwent epigenetic Promote spheroids formation Multi-cellular spheroids formation Effect of tumor spheroids size on internalization of Higher VEGF expression Promote spheroids formation Higher VEGF expression Higher chemoresistance to temozolomide Tumor–stroma cells interaction Higher VEGFR2 expression Higher matrix metalloproteinases (MMPs) exp

Key features • • • • alterations • • • transferrin • • • • • • • • • • • • • • • •

IC V TG TG V TG V EV IC V TG

Human breast adenocarcinoma cells Mouse macrophage cells MDA-MB-231 breast cancer cells Normal mammary epithelial cells MCF 7 human breast cancer cells MDA-MB-231 human breast cancer cells MDA-MB-231 breast cancer cells Primary human bone marrow MSCs MDA-MB-231 breast cancer cells Human fetal osteoblast cell line (hFOB) GSC23 human glioma stem cells Human mesenchymal stem cells (HMSCs) GSC23 human glioma stem cells Glioblastoma-associated macro

Cell types IMR-90 fibroblast cells Breast cancer cells Osteoblasts Glioma stem cells U118 glioma cells Glioblastoma cells (HUVEC) NSCLC PDX cell line Lung CAFs Lung fibroblasts (LFs) Saos-2

Biomaterial ink Modified alginate Gelatin and alginate Gelatin (as template for sacrificial arrays) PEG-DMA (for concave wells) Gelatin, alginate and chitosan GelMA + nHA PEG-DA + PEG + nHA Gelatin, alginate, and fibrinogen Alginate and gelatin Alginate GelMA and gelatin RGD-alginate Hyaluronic acid Collagen-1 GelMA and algMA Agarose and collagen Gelatin and alginate Gelatin, alginate, fibrinogen Hydroxyapatite, poly(dopamine), carbo

Table 1. 3D-bioprinted cancer models Bioprinting technique Cancer model (Co-axial) Breast cancer Extrusion-based Extrusion-based Inkjet Laser-based (direct write) Laser-based Metastatic breast (stereolithography) Laser-based (stereolithography) Extrusion-based (Co-axial) (Co-axial) Extrusion-based Extrusion-based Extrusion-based Inkjet-based Extrusion Extrusion-based Extrusion-based Extrusion Extrusion-based angiogenesis etc.); and,

Bone cancer
Lung cancer

Volume 9 Issue 6 (2023) cancer CNS tumors 379 https://doi.org/10.36922/ijb.1022