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International Journal of Bioprinting                                Design of SLM-Ta artificial vertebral body




               The absence of horizontal orientation constraints   during compression. This accelerated the buckling
            caused the lattice structure to expand outward during   deformation  of  the  vertical  struts,  thereby  reducing  the
            compression. The force and deformation characteristics   load-bearing capacity of the AVB. Therefore, sidewall
            of topological thin-walled and artificial vertebral samples   curvature had different effects on the elastic modulus and
            during compression are displayed in  Figure 17. The   yield strength of the AVB. The focus of this study was to
            topological thin-walled structures of AVB-1 and AVB-  regulate sidewall curvature to develop an AVB exhibiting
            2 featured specific sidewall curvatures, which led to the   optimal mechanical properties.
            formation of plastic hinges at the center of the sidewall   After  implantation,  the  AVB  was  osseointegrated
            under compression. The inward bending of the topological   with the upper and lower cervical vertebral segments,
            thin-walled structure created an interaction force with   thereby performing a load-bearing function and restoring
            the outwardly expanding lattice structure, as shown in    intervertebral height. An AVB requires adequate yield
            Figure 17. In other words, the topological thin-walled   strength, and its elastic modulus should closely match that
            structure restricted the inclination of the peripheral unit   of human bone. This reduces the risk of stress shielding and
            cells of the lattice structure, imposing horizontal constraints   promotes osseointegration. The elastic modulus and yield
            on the internal lattice and inhibiting its outward expansion.   strength of human cortical bone range from 7.7 to 21.8
            The interaction force between the topological thin-walled   GPa and 103 to 222 MPa, respectively.  The yield strengths
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            and lattice structures in AVB-1 and AVB-2 enhanced both   of AVB-1, AVB-2, and AVB-3 were within the range of
            the elastic modulus and the yield strength of the AVB. An   human cortical bone yield strength. This demonstrated
            increase in sidewall curvature led to a higher interaction   that the load-bearing capacities of AVB-1, AVB-2, and
            force, thereby enhancing the load-bearing capacity of   AVB-3 met the requirements for the replacement of
            the AVB.
                                                               diseased vertebrae. As exhibited in  Figure 8, compared
               The topologically thin wall of AVB-3 consisted of   to AVB-1 and AVB-3, AVB-2 exhibited the highest yield-
            vertical struts with zero sidewall curvature. As depicted in   strength-to-elastic-modulus ratio. This design effectively
            Figure 17, the outward expansion of the lattice structures   reduced the stress shielding effect while maximizing the
            provided a source of perturbation for vertical strut buckling   load-bearing function.





































            Figure 17. Schematic representation of the force and deformation characteristics of TTSs and AVBs. Abbreviations: AVB: Artificial vertebral body; TTS:
            Topologically thin-walled structure.


            Volume 11 Issue 4 (2025)                       182                            doi: 10.36922/IJB025150133
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