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International Journal of Bioprinting 3D cell culture model for neural cell analysis
Figure 8. Fluorescence microscopy images showing ROS production in C6 astrocyte-like cells (a) and NG108-15 cells (b) embedded in 3D model particles
after 3 days of culture. Oxidative stress was assessed using the DCFDA probe, which detects ROS activity. The intensity of green fluorescence correlates
with ROS production. (c) DNA damage analysis via γ-H2AX immunofluorescence for C6 astrocyte-like cells exposed to different 3D model particles. Scale
bars = 100 μm. Abbreviations: CoCrMo: Cobalt–chromium–molybdenum; PEEK: Polyetheretherketone; ROS: Reactive oxygen species; ZTA: Zirconia-
toughened alumina.
Volume 11 Issue 4 (2025) 270 doi: 10.36922/IJB025180174
