Page 51 - ITPS-6-2

INNOSC Theranostics and
Pharmacological Sciences Genotoxicity of (4-fluorophenyl) thiazolidin-4-one

Chemical Technology (CSIR-IICT), Hyderabad, for 5. Patel NB, Shaikh FM, 2010, Synthesis and antimicrobial activity
his encouragement and support. KJ acknowledges the of new 4-thiazolidinone derivatives containing 2-amino-6-
Indian Council of Medical Research Government of methoxybenzothiazole. Saudi Pharm J, 18: 129–136.
India for giving ICMR-Senior Research Fellowship (File 6. Vicini P, Geronikaki A, Anastasia K, et al., 2006, Synthesis and
No: 45/15/2018-PHA/TOXI/BMS/OL) to carry out her antimicrobial activity of novel 2-thiazolylimino-5-arylidene-
PhD research. We thank the KIM department CSIR-IICT, 4-thiazolidinones. Bioorg Med Chem, 14: 3859–3864.
Hyderabad, for providing a similarity check and IICT https://doi.org/10.1016/j.bmc.2006.01.043
communication No. IICT/Pubs./2023/147.
7. Ulusoy N, Ergenç N, Ekinci AC, et al., 1996, Synthesis and
Funding anticonvulsant activity of some new arylidenehydrazides and
4-thiazolidinones. Mon Chem/Chem Mon, 127: 1197–1202.
None.
https://doi.org/10.1007/bf00844695
Conflict of interest 8. Archana, Srivastava VK, Kumar A, 2002, Synthesis of newer
thiadiazolyl and thiazolidinonyl quinazolin-4 3H-ones as
All the authors declare that they have no competing potential anticonvulsant agents. Eur J Med Chem, 37: 873–882.
interests.
https://doi.org/10.1016/s0223-5234(02)01389-2
Author contributions 9. Shiradkar MR, Ghodake M, Bothara KG, et al., 2007,
Conceptualization: Sunil Misra, Ravindra M. Kumbhare Synthesis and anticonvulsant activity of clubbed
thiazolidinone-barbituric acid and thiazolidinone-triazole
Formal analysis: Kalpana Javvaji, Jhansi Mamilla derivatives. Arkivoc, 14: 58-74.
Investigation: Jhansi Mamilla, Kalpana Javvaji, Kavya
Lekha Sunkara, Umesh B. Kosurkar https://doi.org/10.3998/ark.5550190.0008.e08
Methodology: Sunil Misra, Ravindra M. Kumbhare 10. Ottana R, Maccari R, Barreca ML, et al., 2005, 5-Arylidene-
Writing – original draft: Kalpana Javvaji, Sunil Misra 2-imino-4-thiazolidinones: Design and synthesis of novel
Writing – review & editing: Sunil Misra, Ravindra M. anti-inflammatory agents. Bioorg Med Chem, 13: 4243–4252.
Kumbhare https://doi.org/10.1016/j.bmc.2005.04.058

Ethics approval and consent to participate 11. Boyd MR, Paull KD, 1995, Some practical considerations
and applications of the national cancer institute in vitro
Not applicable. anticancer drug discovery screen. Drug Dev Res, 34: 91–109.
Consent for publication https://doi.org/10.1002/ddr.430340203
12. Carter PH, Scherle PA, Muckelbauer JA, et al., 2001,
Not applicable.
Photochemically enhanced binding of small molecules to
Availability of data the tumor necrosis factor receptor-1 inhibits the binding of
TNF-alpha. Proc Natl Acad Sci, 98: 11879–11884.
Supporting data can be obtained from corresponding https://doi.org/10.1073/pnas.211178398
author following formal request.
13. Cutshall NS, O’Day C, Prezhdo M, 2005, Rhodanine
References derivatives as inhibitors of JSP-1. Bioorg Med Chem Lett,
15: 3374–3379.
1. Brown FC, 1961, 4-Thiazolidinones. Chem Rev, 61: 463–521.
https://doi.org/10.1016/j.bmcl.2005.05.034
2. Jain AK, Vaidya A, Ravichandran V, et al., 2012, Recent
developments and biological activities of thiazolidinone 14. Look GC, Schullek JR, Holmes CP, et al., 1996, The
derivatives: A review. Bioog Med Chem, 20: 3378–3395. identification of cyclooxygenase-1 inhibitors from
4-thiazolidinone combinatorial libraries. Bioorg Med Chem
https://doi.org/10.1016/j.bmc.2012.03.069 Let, 6: 707–712.
3. Tripathi AC, Gupta SJ, Fatima G, et al., 2014, 4-Thiazolidinones: https://doi.org/10.1016/0960-894x(96)00097-2
The advances continue. Eur J Med Chem, 72, 52–77.
15. Barreca ML, Chimirri A, De Luca L, et al., 2001, Discovery
https://doi.org/10.1016/j.ejmech.2013.11.017 of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV-1
4. Thomas B, LS A, Harindran J, 2014, Novel Mannich bases agents. Bioorg Med Chem Lett, 11: 1793–1796.
of 4-thiazolidinone derivatives as antitubercular agents. Int J https://doi.org/10.1016/s0960-894x(01)00304-3
Res Pharm Chem, 4: 351–359.
16. Rao A, Carbone A, Chimirri A, et al., 2002, Synthesis and
https://doi.org/10.1016/j.jsps.2010.05.002 anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-(thi)one

Volume 6 Issue 2 (2023) 8 https://doi.org/10.36922/itps.0618