Page 12 - ITPS-8-2

INNOSC Theranostics and
Pharmacological Sciences AMPK in metabolism, energy and aging

Table 2. (Continued)
Compound Chemical structure AMPK activation mechanism References
Berberine Respiratory chain blockage (complex I) 59
Increase in AMP/ATP ratio

Curcumine Increase in AMP/ATP ratio (action on mitochondrial 60
F1F0-ATPase/ATP synthase)

Ginsenoside Rb1 Increase in AMP/ATP ratio (unknown mechanism) 61

α-lipoic acid Unknown mechanism 62

EGCG Respiratory chain blockage. Increase AMP level 63

Cryptotanshinone Increase ROS (unknown mechanism) 64

Capsaicin Not specified 65

Arctigenin LKB1/CaMKK 66

Chitooligosaccharides Not specified 67

(Cont’d...)

Volume 8 Issue 2 (2025) 6 doi: 10.36922/itps.4852