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Journal of Clinical and
            Basic Psychosomatics                                                   Evaluation of biopsychosocial factors



            and SF-36 (global and mental health components) scores   the participants (male or female) was recorded, with the
            with the 1-year mortality rate, assessing the relationship   proportion being 43% female and 57% male.
            between anxiety and depression with mortality in a chronic   The remaining 30% of patients (36 individuals)
            pain cancer population. A Kruskal–Wallis test was used to   were unmarried. Of these, 5% were single (n  = 6), 5%
            explore the relationship between HADS with marital status   were divorced, and 20% were widowed (n = 24). These data
            (single, married, divorced, or widowed). A Mann-Whitney   are presented in Figure 1.
            test was performed to assess the relationship between
            HADS with self-sufficiency (autonomous or dependent).  Concerning individual  autonomy or self-sufficiency,
                                                               most patients – specifically 63.6% (n = 77) – considered
              Canonical correlation analysis (CCA) was used to   themselves autonomous or self-sufficient, while 36.4%
            evaluate the relationships among different constructs of   (n = 43) reported being dependent (Figure 2).
            anxiety, depression, QoL, and pain was carried out using.
            The dimensions of each questionnaire were treated as   The statistical analysis of correlations revealed
            primary  variables.  For the BPI,  the  pain  dimension  and   that  depression  is associated  with marital  status.
            interference dimensions were considered, while for the   Depression was  more  pronounced in  widowed  or
            HADS, the anxiety and depression dimensions were used.   divorced individuals  (P  <  0.05), less significant in
            In the SF-36 questionnaire, the following dimensions were   unmarried  individuals (P  =  0.042), and not relevant
            included: “physical function,” “physical performance,”   in the married group (P = 0.653). The values presented in
            “body pain,” “general health,” “vitality,” “social function,”   Table 1 represent the mean scores ± standard deviation
            “emotional performance,” and “mental health.”      for depression and anxiety in married  and unmarried
                                                               populations. These values reflect the average scores, based
              The relationship between the BPI and HADS        on the maximum possible score of 21 on the HADS for
            questionnaires was evaluated first. A  CCA was then   depression and anxiety. A 95% confidence level was used
            performed to examine the relationship between the   to determine statistical significance (Table 1).
            dimensions of these two questionnaires and those of the
            SF-36. A composite construct was created by combining   The  results  related  to  marital  status  reveal  a clear
            the dimensions of the BPI and the HADS, which were   imbalance between the number of married and unmarried
            correlated with the dimensions of the SF36. The statistical   individuals. Although the statistical evaluation considered
            significance of the canonical correlation was assessed using
            Wilks’ Lambda. The strength of the correlation between the
            canonical variables was used to explore the relationships
            between the constructs. In addition, the correlations
            between the original  variables  (BPI/HADS  and SF-36
            dimensions) and the significant canonical variables were
            examined. In cases where multiple canonical variables
            were identified, the construct with the highest correlation
            was interpreted as the most likely construct, based on its
            relationship with the original variables.
            3. Results and discussion                          Figure 1. Marital status of 120 patients: 84 married (70%) and 36 non-
            The results were obtained through statistical correlations   married (30%). Among the non-married patients, 6 were single (5%), 24
            of the variables analyzed from the three questionnaires   were widowed (20%), and 6 were divorced (5%).
            selected for this study: HADS, BPI, and SF-36. These
            questionnaires evaluate the dimensions of depression and
            anxiety, the global dimensions related to pain, and the
            QoL, respectively. A  95% confidence level was applied,
            with results considered statistically significant at P < 0.05.

              Regarding the demographic data, the study sample
            consisted of 120 cancer patients. Of these, 70%
            (84  patients) were classified as “married to partner,”
            without distinguishing between the type of relationship
            (heterosexual  or  homosexual)  or  legal/religious  status   Figure 2. Individual autonomy status of 120 patients: 77 self-sufficient
            (civil marriage or “de facto” union). Only the gender of   (63.6%) and 43 dependent patients (36.4%).


            Volume 3 Issue 2 (2025)                         62                              doi: 10.36922/jcbp.4097
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