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Journal of Clinical and Translational Research 2024; 10(2): 119-140




                                        Journal of Clinical and Translational Research

                                               Journal homepage: http://www.jctres.com/en/home


        REVIEW ARTICLE

        Identification of the essential and critical factors of decision-making for

        COVID-19 patient management: a mixed-method study



        Hamidreza Abtahi , Sharareh Rostam Niakan Kalhori , Amir Hossein Abooei , Moloud Taheriyan ,
                                                                                             2
                       1
                                                      2,3
                                                                            4
        Seyed Mohammad Ayyoubzadeh , Marsa Gholamzadeh *, Elham Sadat Mousavinasab , Shahideh Amini ,
                                     2
                                                                                                    6
                                                                                     5
                                                         2
        Mojghan Mohajeri Iravani , Alireza Bahramnejad 8
                              7
        1 Department of Pulmonary and Critical Care, Thoracic Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences,
        Tehran, Iran,  Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran,
                  2
        Iran,  Department of Computer Science, Peter L. Reichertz Institute for Medical Informatics, Technical University of Braunschweig, Braunschweig,
            3
        Germany,  Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy,  Department of Health Information Management,
                                                                             5
               4
        School of Allied Medical Sciences, Kashan University of Medical Science, Kashan, Iran,  Department of Clinical Pharmacy, Faculty of Pharmacy,
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        Tehran University of Medical Sciences, Tehran, Iran,  Department of Anesthesiology and Critical Care, Aja University of Medical Sciences, Tehran,
                                              7
        Iran,  Department of Emergency Medicine, Iran University of Medical Sciences, Tehran, Iran
            8
        ARTICLE INFO                        Abstract
        Article history:                    Background: Understanding the contributing factors for decision-making based on the disease stage
        Received: December 21, 2022         is highly crucial to improving patient care.
        Accepted: October 27, 2023          Aim: This study aimed to identify the critical and essential factors to enhance clinical decision-making
        Published Online: March 20, 2024    for COVID-19 patients.
                                            Methods: This mixed-method research was conducted in two phases. In the first phase, a systematic
        Keywords:                           literature  review  was  performed  using  defined  search  strategies  across  four  databases,  including
        COVID-19                            PubMed,  Scopus,  Web  of  Science,  and  IEEE.  A  total  of  136  studies  were  obtained.  Next,  a
        Coronavirus                         questionnaire-based survey was conducted to validate the findings from the review and to categorize
        Decision-making                     the factors into essential and critical factors. The content validity ratio was used to categorize the
        Triage                              factors accordingly. The identified factors were classified into six main categories based on the stages
        Uncertainty                         of care and the corresponding decision-making.
        Patient management                  Results: The expert panel consisted of 10 clinicians from various fields. The potential factors were
                                            categorized into six categories. A total of 293 factors were found in the literature review. The findings
                                            of the consensus survey revealed 10 factors related to the decisions on the length of stay, eight factors
        *Corresponding authors:             for ward referral decisions, one factor for decisions on home referrals, six factors for deterioration
        Marsa Gholamzadeh                   diagnosis decisions, two factors for discharge decisions, and 10 factors for decisions on intensive care
        Department of Health Information Management,   unit referrals. In addition, the study identified respiratory rate, oxygen saturation at administration,
        School of Allied Medical Sciences, Tehran
        University of Medical Sciences, Fardanesh   arterial oxygen pressure, sequential organ failure assessment score, and glomerular filtration rate as
        Alley, Qods Street, Tehran, Iran.   significant decision-making factors for COVID-19 patient management.
        Email: marsa.gholamzadeh@yahoo.com  Conclusion: For medical emergencies (e.g., COVID-19 management), fewer but more significant
                                            factors  may  increase  the  efficiency  of  decision-making,  thereby  improving  the  quality  of  patient
        © 2024 Author(s). This is an Open-Access   management. On this basis, this study identified the essential and critical factors for decision-making
        article distributed under the terms of the   at different stages of COVID-19 patient management.
        Creative Commons Attribution-Noncommercial   Relevance for Patients: This study identified the most important factors in diagnosing the deterioration
        License, permitting all non-commercial use,   of COVID-19 patients to improve the treatment outcome of COVID-19 patients.
        distribution, and reproduction in any medium,
        which provided that the original work is
        properly cited.
                                            1. Introduction
                                              The COVID-19 pandemic has been known as a global challenge that requires inclusive
                                            approaches  to  control.  COVID-19  is  caused  by  a  new  virus  that  was  officially  named
                                                 DOI: https://doi.org/10.36922/jctr.22.00226
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