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Journal of Clinical and

                                                                  Translational Research



                                        CASE REPORT
                                        The importance of clinical and radiological

                                        follow-up after conservative treatment of
                                        iatrogenic type A aortic dissection: A case report



                                        Lars Niclauss , Filip Dulguerov* , Ziyad Gunga , Anna Nowacka ,
                                        and Matthias Kirsch
                                        Department  of Cardiovascular Surgery, University Hospital  of Lausanne, Lausanne,  Vaud,
                                        Switzerland




                                         Abstract
                                        Background: Iatrogenic type  A dissections can be managed conservatively, but
                                        clear guidelines for treatment are lacking. Case presentation: This case illustrates
                                        a borderline situation that necessitated a change in treatment approach. A patient
                                        underwent endo-prosthetic treatment for an aneurysm. During the insertion of
                                        a guiding catheter through the axillary artery, the ascending aorta was dissected,
            *Corresponding author:      with contrast injected into the vascular wall. Due to the mechanism of injury and the
            Filip Dulguerov             absence of an intra-aortic intimal tear (as evidenced by contrast stagnation in the
            (filip.dulguerov@chuv.ch)   false lumen), conservative management was initially chosen. A follow-up computed
            Citation: Niclauss L, Dulguerov F,   tomography (CT) scan showed complete resolution after 1  month. However,
            Gunga Z, Nowacka A, Kirsch M.   10 days later, the patient was readmitted with acute chest pain, and a new CT scan
            The importance of clinical and
            radiological follow-up after   revealed an acute dissection, with a free-moving intimal flap in the ascending
            conservative treatment of   aorta, requiring emergency surgery. Current guidelines recommend surgery for
            iatrogenic type A aortic dissection:   iatrogenic type A dissections that extend or propagate several centimeters into the
            A case report. J Clin Transl Res.
            2025;11(1):73-76.           ascending aorta. However, these guidelines do not account for the mechanism of
            doi: 10.36922/jctr.24.00048  injury, the localization, or the size of the intimal tear. Conclusion: In this case, the
            Received: July 30, 2024     assumption of spontaneous healing with an intact intima was initially supported.
                                        However, further developments highlight the importance of clinical and radiological
            1st revised: September 19, 2024  follow-up, regardless of the injury’s mechanism. Relevance for patients: Iatrogenic
            2nd revised: November 11, 2024  aortic dissection is a highly complex condition that requires close monitoring and, if
            Accepted: December 25, 2024  necessary, a reassessment of the chosen treatment strategy.
            Published online: February 3,
            2025                        Keywords: Intravascular catheterization; Intimal tear; Iatrogenic type A aortic dissection;
            Copyright: © 2025 Author(s).   Mechanism of injury; Conservative management; Clinical follow-up; Radiological
            This is an open-access article   follow-up; Treatment guidelines
            distributed under the terms of the
            Creative Commons Attribution
            Non-Commercial 4.0 International
            (CC BY-NC 4.0), which permits all
            non-commercial use, distribution,   1. Background
            and reproduction in any medium,
            provided the original work is   Iatrogenic type  A aortic dissections due to intravascular catheterization are often
            properly cited.             managed conservatively, in contrast to iatrogenic dissections caused directly by open-
            Publisher’s Note: AccScience   heart surgery or transcatheter aortic valve implantation. However, clear treatment
            Publishing remains neutral with   guidelines for this clinical context, which could guide the decision to pursue or avoid
            regard to jurisdictional claims in
            published maps and institutional   a conservative approach, are lacking. The present case illustrates a borderline situation
            affiliations                that ultimately led to a change in the treatment strategy.


            Volume 11 Issue 1 (2025)                        73                            doi: 10.36922/jctr.24.00048
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